ArticlePsychiatry research2012
Abnormal functional brain asymmetry in depression: evidence of biologic commonality between major depression and dysthymia.
Article in Psychiatry research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 38 citations in OpenAlex.
- Hemispheric asymmetry in depressive symptoms is associated with sex-divergent functional brain connectivity patterns.iScience · 2026Article
- Exploring sexual dimorphism in basal forebrain volume changes during aging and neurodegenerative diseases.iScience · 2024Article
- Altered asymmetry of functional connectome gradients in major depressive disorder.Frontiers in neuroscience · 2024Article
- Revisiting Hemispheric Asymmetry in Mood Regulation: Implications for rTMS for Major Depressive Disorder.Brain sciences · 2022Review
- Different patterns of white matter microstructural alterations between psychotic and non-psychotic bipolar disorder.PloS one · 2022Article
- Sleep-Dependent Anomalous Cortical Information Interaction in Patients With Depression.Frontiers in neuroscience · 2021Article
- Frontotemporal asymmetry in socioemotional behavior: A pilot study in frontotemporal dementia.Social neuroscience · 2020Article
- Evaluating the diagnostic utility of applying a machine learning algorithm to diffusion tensor MRI measures in individuals with major depressive disorder.Psychiatry research. Neuroimaging · 2017Article
- Global brain asymmetry is increased in schizophrenia and related to avolition.Acta psychiatrica Scandinavica · 2017Article
- Development of human white matter fiber pathways: From newborn to adult ages.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2016Article
- Lateralization for speech predicts therapeutic response to cognitive behavioral therapy for depression.Psychiatry research · 2015Article
- The effects of prenatal stress on alpha4 beta2 and alpha7 hippocampal nicotinic acetylcholine receptor levels in adult offspring.Developmental neurobiology · 2013Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Prior studies have found abnormalities of functional brain asymmetry in patients having a major depressive disorder (MDD). This study aimed to replicate findings of reduced right hemisphere advantage for perceiving dichotic complex tones in depressed patients, and to determine whether patients having "pure" dysthymia show the same abnormality of perceptual asymmetry as MDD. It also examined gender differences in lateralization, and the extent to which abnormalities of perceptual asymmetry in depressed patients are dependent on gender. Unmedicated patients having either a MDD (n=96) or "pure" dysthymic disorder (n=42) and healthy controls (n=114) were tested on dichotic fused-words and complex-tone tests. Patient and control groups differed in right hemisphere advantage for complex tones, but not left hemisphere advantage for words. Reduced right hemisphere advantage for tones was equally present in MDD and dysthymia, but was more evident among depressed men than depressed women. Also, healthy men had greater hemispheric asymmetry than healthy women for both words and tones, whereas this gender difference was not seen for depressed patients. Dysthymia and MDD share a common abnormality of hemispheric asymmetry for dichotic listening.
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