ArticleAging and disease2011
Finding Balance: T cell Regulatory Receptor Expression during Aging.
Article in Aging and disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- DJ-1 depletion prevents immunoaging in T-cell compartments.EMBO reports · 2022Article
- Article
- The immunoinhibitory PD-1/PD-L1 pathway in inflammatory blood vessel disease.Journal of leukocyte biology · 2018Review
- Analysis of cytomegalovirus-specific T-cell responses in patients with hypertension: comparison of assay methods and antigens.Clinical hypertension · 2018Article
- Immunosenescence: the Role of Aging in the Predisposition to Neuro-Infectious Complications Arising from the Treatment of Multiple Sclerosis.Current neurology and neuroscience reports · 2017Review
- Continuous Dual Resetting of the Immune Repertoire as a Basic Principle of the Immune System Function.Journal of immunology research · 2017Review
- The life cycle of a T cell after vaccination - where does immune ageing strike?Clinical and experimental immunology · 2017Review
- T cell senescence and cardiovascular diseases.Clinical and experimental medicine · 2016Review
- Cytomegalovirus Infection and Memory T Cell Inflation.Immune network · 2015Review
- Large-Scale and Comprehensive Immune Profiling and Functional Analysis of Normal Human Aging.PloS one · 2015Article
- Coordinated regulation of NK receptor expression in the maturing human immune system.Journal of immunology (Baltimore, Md. : 1950) · 2014Article
- Understanding immunosenescence to improve responses to vaccines.Nature immunology · 2013Review
- Immunosenescence, aging, and systemic lupus erythematous.Autoimmune diseases · 2013Review
- The janus head of T cell aging - autoimmunity and immunodeficiency.Frontiers in immunology · 2013Article
- Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment.Seminars in immunology · 2012Review
- Immune aging and challenges for immune protection of the graying population.Aging and disease · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Aging is associated with a variety of changes to immune responsiveness. Reduced protection against infection, reduced responses to vaccination and increased risk of autoimmunity are all hallmarks of advanced age. Here we consider how changes in the expression of regulatory receptors on the T cell surface contribute to altered immunity during aging.
Indexed as
Identifiers
22396890PMC3295076What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.