ArticlePloS one2012
Candida dubliniensis: an appraisal of its clinical significance as a bloodstream pathogen.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Antifungal and Antivirulence Activity of Alizarin againstACS infectious diseases · 2026Article
- Cases of endophthalmitis caused by Candida albicans and Candida dubliniensis identified via internal transcribed spacer deep sequencing.BMC ophthalmology · 2024Article
- Candida dubliniensis meningitis in an immunocompetent patient: A case report and review of the literature.eNeurologicalSci · 2024Article
- A highly conserved tRNA modification contributes toMicrobiology spectrum · 2024Article
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- Septic arthritis caused byMedical mycology case reports · 2024Article
- Exploring the Biology, Virulence, and General Aspects ofInfection and drug resistance · 2024Review
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- Alteration of Cell Membrane Permeability by Cetyltrimethylammonium Chloride Induces Cell Death in Clinically ImportantInternational journal of environmental research and public health · 2022Article
- A New Variant of Mutational and Polymorphic Signatures in theInfection and drug resistance · 2022Article
- Catechol thwarts virulent dimorphism in Candida albicans and potentiates the antifungal efficacy of azoles and polyenes.Scientific reports · 2021Article
- Differentiation ofCurrent medical mycology · 2021Article
- The Role of Bacterial and Fungal Human Respiratory Microbiota in COVID-19 Patients.BioMed research international · 2021Review
- Colovesicular fistula fromJournal of community hospital internal medicine perspectives · 2020Article
- Antifungal drug susceptibility, molecular basis of resistance to echinocandins and molecular epidemiology of fluconazole resistance among clinical Candida glabrata isolates in Kuwait.Scientific reports · 2020Article
- Fatal chronic meningitis caused byMedical mycology case reports · 2020Article
- Case Report:Frontiers in neurology · 2020Article
- First Reported Case ofCase reports in cardiology · 2020Article
- Oral colonization by Candida species and associated factors in HIV-infected patients in Ahvaz, southwest Iran.Epidemiology and health · 2020Article
- Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
A nine-year prospective study (2002-2010) on the prevalence of Candida dubliniensis among Candida bloodstream isolates is presented. The germ tube positive isolates were provisionally identified as C. dubliniensis by presence of fringed and rough colonies on sunflower seed agar. Subsequently, their identity was confirmed by Vitek2 Yeast identification system and/or by amplification and sequencing of the ITS region of rDNA. In all, 368 isolates were identified as C. dubliniensis; 67.1% came from respiratory specimens, 11.7% from oral swabs, 9.2% from urine, 3.8% from blood, 2.7% from vaginal swabs and 5.4% from other sources. All C. dubliniensis isolates tested by Etest were susceptible to voriconazole and amphotericin B. Resistance to fluconazole (≥8 µg/ml) was observed in 2.5% of C. dubliniensis isolates, 7 of which occurred between 2008-2010. Of note was the diagnosis of C. dubliniensis candidemia in 14 patients, 11 of them occurring between 2008-2010. None of the bloodstream isolate was resistant to fluconazole, while a solitary isolate showed increased MIC to 5-flucytosine (>32 µg/ml) and belonged to genotype 4. A review of literature since 1999 revealed 28 additional cases of C. dubliniensis candidemia, and 167 isolates identified from blood cultures since 1982. In conclusion, this study highlights a greater role of C. dubliniensis in bloodstream infections than hitherto recognized.
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