Evidence map›Paper›PMID 22396450›Full record

ReviewEndocrinology2012

Minireview: animal models and mechanisms of ovarian cancer development.

Lisa K Mullany, JoAnne S Richards

Abstract readReview
In one paragraph

Review in Endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Review
  3. The hallmarks of ovarian cancer: proliferation and cell growth.EJC supplements : EJC : official journal of EORTC, European Organization for Research and Treatment of Cancer ... [et al.] · 2020
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The promise and challenge of ovarian cancer models.Translational cancer research · 2015
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lisa K MullanyDepartment of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.
JoAnne S Richards

Funding

TRANSGENIC MOUSE MODELS TO STUDY OVARIAN FUNCTIONU54HD007495 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI RICHARDS, JOANNE STEWART · 1998 to 2013
$19.9M
LH ACTION IN OVARIAN CELL DIFFERENTIATIONR37HD016229 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI RICHARDS, JOANNE S. · 1998 to 2007
$2.0M
LH ACTION IN OVARIAN CELL DIFFERENTIATIONR01HD016229 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI RICHARDS, JOANNE STEWART · 1985 to 2013
$1.9M
GROWTH AND DIFFERENTIATION IN EUKARYOTEST32HD007495 · NICHD · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI KINTNER, CHRISTOPHER ROBERT · 1995 to 2009
$1.6M
LH Action in Ovarian Cell DifferentiationR56HD016229 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI RICHARDS, JOANNE STEWART · 2008 to 2008
$326k
TRANSGENIC ANIMAL--COREP30HD007495 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI GLASSER, STANLEY R · 1985 to 1997
–
NICHD NIH HHS HD-16229NICHD NIH HHS P30 HD007495NICHD NIH HHS R01 HD016229NICHD NIH HHS R37 HD016229NICHD NIH HHS R56 HD016229NICHD NIH HHS T32 HD007495NICHD NIH HHS U54 HD007495NICHD NIH HHS U54-HD07495
6 · The paper itself

Abstract

Ovarian cancer in women is a complex and deadly disease, where the molecular events that initiate and control tumor formation remain poorly defined. Therefore, mouse models provide one approach for determining the mechanisms by which specific oncogenic factors cause ovarian surface epithelial cell and granulosa cell transformation. This minireview summarizes the phenotypes of current mouse models that have been generated and some of the underlying mechanisms they have provided.

Indexed as

Disease Models, AnimalAnimalsCarcinoma, Ovarian EpithelialCell Transformation, NeoplasticFemaleGranulosa Cell TumorMiceNeoplasms, Glandular and EpithelialOvarian NeoplasmsPhenotypeTumor Suppressor Protein p53Tumor Suppressor Protein p53

Identifiers

PMID22396450
PMCPMC3320247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.