Evidence map›Paper›PMID 22395958›Full record

ArticleEcoHealth2012

Failure to detect simian immunodeficiency virus infection in a large Cameroonian cohort with high non-human primate exposure.

Cyrille F Djoko, Nathan D Wolfe, Avelin F Aghokeng, Matthew Lebreton, Florian Liegeois, Ubald Tamoufe, Bradley S Schneider, Nancy Ortiz, Wilfred F Mbacham, Jean K Carr and 7 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in EcoHealth, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. The potential impacts of human genetics on virus emergence.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 3 countries.

Cyrille F DjokoGlobal Viral Forecasting, Yaoundé, Cameroon.
Nathan D Wolfe
Avelin F Aghokeng
Matthew Lebreton
Florian Liegeois
Ubald Tamoufe
Bradley S Schneider
Nancy Ortiz
Wilfred F Mbacham
Jean K Carr
Anne W Rimoin
Joseph N Fair
Brian L Pike
Eitel Mpoudi-Ngole
Eric Delaporte
Donald S Burke
Martine Peeters
Global Viral · USInstitut de Recherche pour le Développement · FRInstitut de Recherches Médicales et d’Etudes des Plantes Médicinales · CMPittsburg State University · USUniversité de Montpellier · FRUniversité de Yaoundé I · CMUniversity of California System · USUniversity of Maryland, Baltimore · US

Funding

TUBERCULOSIS INTERNATIONAL TRAINING AND RESEARCH PROGRAMD43TW000010 · FIC · JOHNS HOPKINS UNIVERSITY · PI BEYRER, CHRISTOPHER C. · 1988 to 2012
$19.8M
NIH Director's Pioneer Award (RMI)DP1OD000370 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOLFE, NATHAN D · 2005 to 2009
$3.4M
FIC NIH HHS 2 D 43 TW000010-16/17NIH HHS DP1-OD000370
6 · The paper itself

Abstract

Hunting and butchering of wildlife in Central Africa are known risk factors for a variety of human diseases, including HIV/AIDS. Due to the high incidence of human exposure to body fluids of non-human primates, the significant prevalence of simian immunodeficiency virus (SIV) in non-human primates, and hunting/butchering associated cross-species transmission of other retroviruses in Central Africa, it is possible that SIV is actively transmitted to humans from primate species other than mangabeys, chimpanzees, and/or gorillas. We evaluated SIV transmission to humans by screening 2,436 individuals that hunt and butcher non-human primates, a population in which simian foamy virus and simian T-lymphotropic virus were previously detected. We identified 23 individuals with high seroreactivity to SIV. Nucleic acid sequences of SIV genes could not be detected, suggesting that SIV infection in humans could occur at a lower frequency than infections with other retroviruses, including simian foamy virus and simian T-lymphotropic virus. Additional studies on human populations at risk for non-human primate zoonosis are necessary to determine whether these results are due to viral/host characteristics or are indicative of low SIV prevalence in primate species consumed as bushmeat as compared to other retroviruses in Cameroon.

Indexed as

AnimalsCameroonCohort StudiesDisease Transmission, InfectiousFood MicrobiologyHumansMeatPrimatesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusZoonoses

Identifiers

PMID22395958
OpenAlexW2054440192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.