ArticlePsychopharmacology2012
Antidepressants and lethal violence in the Netherlands 1994-2008.
Article in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.
- Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports.BMJ (Clinical research ed.) · 2016Pooled it
- Pooled it
- Increased Prescribing of Psychotropic Drugs or School-Based Services for Children with Disabilities? Associations of These Self-control-Boosting Strategies with Juvenile Violence at the State Level.Journal of developmental and life-course criminology · 2023Article
- Is Sertraline a Good Pharmacological Strategy to Control Anger? Results of a Systematic Review.Behavioral sciences (Basel, Switzerland) · 2019Review
- Selective serotonin re-uptake inhibitors and the risk of violent suicide: a nationwide postmortem study.European journal of clinical pharmacology · 2019Article
- Antidepressant Regulatory Warnings, Prescription Patterns, Suicidality and Other Aggressive Behaviors in Major Depressive Disorder and Anxiety Disorders.The Psychiatric quarterly · 2016Article
- [Interpersonal violence in the context of affective and psychotic disorders].Der Nervenarzt · 2016Review
- Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study.PLoS medicine · 2015Article
- Psychotropic drugs and homicide: A prospective cohort study from Finland.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2015Article
- [Antidepressive agents and suicidal tendencies].Der Nervenarzt · 2014Review
- Antidepressants and lethal violence in the Netherlands.Psychopharmacology · 2012Article
- Selective Serotonin Reuptake Inhibitors (SSRIs) and Their Effect on Patient Aggression in Adult Patients in a State Psychiatric Facility: A Retrospective Analysis.Innovations in clinical neuroscienceArticle
Corrections and comments
- Commented on by
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleThere is an ongoing discussion on the relation between risk of violent behaviour and the use of antidepressants. The claim that the use of antidepressants can cause violent behaviour would gain credibility if a positive association between the two could be established.
objectiveThe objective of this study is to evaluate the relationship between homicide, suicide and homicide-suicide rates and the rates of antidepressant use by gender and age group.
methodNationwide data from the Netherlands on antidepressant prescriptions (ADs, SSRI and venlafaxine) and lethal violence were analysed over the 15-year period from 1994 to 2008.
resultsThe findings indicated a significant negative association between lethal violence (homicide and suicide) and prescription of antidepressants in the Netherlands, indicating that in a period in which the exposure of the Dutch population to antidepressants increased, rates of lethal violence decreased.
conclusionsThese data lend no support for an important role of antidepressant use in lethal violence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.