Evidence map›Paper›PMID 22394709›Full record

ArticleJournal of clinical research in pediatric endocrinology2012

Vitamin D deficiency in children and adolescents.

Nesibe Andıran, Nurullah Çelik, Halise Akça, Güzide Doğan

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it, 187 citations in OpenAlex.

  1. Pooled it
  2. Safety and Efficacy of Stosstherapy in Nutritional Rickets.Journal of clinical research in pediatric endocrinology · 2017
    Trial
  3. Are Growing Pains Related to Vitamin D Deficiency? Efficacy of Vitamin D Therapy for Resolution of Symptoms.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2015
    Trial
  4. Effect of vitamin D therapy in addition to amitriptyline on migraine attacks in pediatric patients.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014
    Trial
  5. Impact of vitamin D fortified milk supplementation on vitamin D status of healthy school children aged 10-14 years.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013
    Trial
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  19. Evaluation of bone health in patients with mucopolysaccharidosis.Journal of bone and mineral metabolism · 2022
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nesibe AndıranFatih University Faculty of Medicine, Department of Pediatric Endocrinology, Ankara, Turkey. haliseakca@gmail.com
Nurullah Çelik
Halise Akça
Güzide Doğan
Fatih University · TRAnkara University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVitamin D deficiency is an important health problem in both developed and developing countries. Recent reports on the extraskeletal effects of vitamin D have led to increased interest in prevalence studies on states of deficiency/insufficiency of vitamin D. The aim of this study was to determine the frequency of vitamin D deficiency and insufficiency in children and adolescents residing in Ankara, Turkey and to investigate the factors associated with low vitamin D status.

methodsA total of 440 children and adolescents aged between 0 and 16 years were enrolled in this study. The subjects were divided into three groups according to their vitamin D status (deficiency ≤15 ng/mL; insufficiency: 15-20 ng/mL; sufficiency ≥20 ng/mL) and also according to their age (preschool<5 years; middle childhood: 5-10 years; adolescence: 11-16 years).

resultsOverall, 40% of the subjects were found to have 25 hydroxy vitamin D [25(OH)D] levels of less than 20 ng/mL. The levels indicated a deficiency state in 110 subjects (25%) and insufficiency - in 66 (15%). The rate of vitamin D deficiency was higher in girls, regardless of age. 25(OH)D levels correlated negatively with age (r=-0.48, p<0.001), body mass index (BMI) (r=-0.20, p=0.001) and intact parathyroid hormone (iPTH) level (r=-0.31, p=0.001). A positive correlation was observed between 25(OH)D and serum ferritin levels (r=0.15, p=0.004).

conclusionsThe high frequency of vitamin D deficiency in childhood (especially among adolescent girls) indicates a need for supplementation and nutritional support.

Indexed as

AdolescentAge FactorsAnalysis of VarianceBody Mass IndexChildChild, PreschoolFemaleFerritinsHumansInfant, NewbornMaleParathyroid HormonePrevalenceSex FactorsTurkeyVitamin D25-hydroxyvitamin DFerritinsParathyroid HormoneVitamin D

Identifiers

PMID22394709
PMCPMC3316459
OpenAlexW2052666025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.