ReviewRadiation oncology (London, England)2012
Iodine-125 brachytherapy for brain tumours--a review.
Review in Radiation oncology (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.
- Beyond surgical resection: evaluating stereotactic brachytherapy iodine-125 for low-grade gliomas: a systematic review and meta-analysis.Neurosurgical review · 2024Pooled it
- A novel three-dimensional template combined with MR-guidedRadiation oncology (London, England) · 2020Trial
- Iodine-125 brachytherapy improved overall survival of patients with inoperable stage III/IV non-small cell lung cancer versus the conventional radiotherapy.Medical oncology (Northwood, London, England) · 2015Trial
- Dosimetric Impacts of Source Migration, Radioisotope Type, and Decay with Permanent Implantable Collagen Tile Brachytherapy for Brain Tumors.Technology in cancer research & treatmentTrial
- A prospective study of minimally invasive keyhole craniotomy and stereotactic brachytherapy for new brain oligometastases.Journal of neuro-oncology · 2025Article
- Feasibility analysis and efficacy evaluation of computed tomography-guided microwave ablation combined with radioactiveWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Brachytherapy in Brain Metastasis Treatment: A Scoping Review of Advances in Techniques and Clinical Outcomes.Cancers · 2024Article
- Ultrasmall Gold Nanoparticles Radiolabeled with Iodine-125 as Potential New Radiopharmaceutical.ACS applied bio materials · 2024Article
- Future Prospective of Radiopharmaceuticals from Natural Compounds Using Iodine Radioisotopes as Theranostic Agents.Molecules (Basel, Switzerland) · 2022Review
- Patient-specific radiological protection precautions following Cs collagen embedded Cs-131 implantation in the brain.Journal of applied clinical medical physics · 2022Article
- The role of cesium-131 brachytherapy in brain tumors: a scoping review of the literature and ongoing clinical trials.Journal of neuro-oncology · 2022Article
- The Chemical Scaffold of Theranostic Radiopharmaceuticals: Radionuclide, Bifunctional Chelator, and Pharmacokinetics Modifying Linker.Molecules (Basel, Switzerland) · 2022Review
- Article
- Iodine-125 brachytherapy treatment for newly diagnosed brain metastasis in non-small cell lung cancer: A biocentric analysis.Frontiers in oncology · 2022Article
- A Robust Oxygen Microbubble Radiosensitizer for Iodine-125 Brachytherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Radiation necrosis after a combination of external beam radiotherapy and iodine-125 brachytherapy in gliomas.Radiation oncology (London, England) · 2021Article
- ExtracranialFrontiers in neuroscience · 2021Article
- Radioactive Iodine-125 in Tumor Therapy: Advances and Future Directions.Frontiers in oncology · 2021Review
- Long-term outcome of stereotactic brachytherapy with temporary Iodine-125 seeds in patients with WHO grade II gliomas.Radiation oncology (London, England) · 2020Article
- Synthesis and Characterization of a Specific Iodine-125-Labeled TRPC5 Radioligand.ChemMedChem · 2020Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iodine-125 brachytherapy has been applied to brain tumours since 1979. Even though the physical and biological characteristics make these implants particularly attractive for minimal invasive treatment, the place for stereotactic brachytherapy is still poorly defined.An extensive review of the literature has been performed, especially concerning indications, results and complications. Iodine-125 seeds have been implanted in astrocytomas I-III, glioblastomas, metastases and several other tumour entities. Outcome data given in the literature are summarized. Complications are rare in carefully selected patients.All in all, for highly selected patients with newly diagnosed or recurrent primary or metastatic tumours, this method provides encouraging survival rates with relatively low complication rates and a good quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.