ReviewExperimental lung research2012
VEGF levels in humans and animal models with RDS and BPD: temporal relationships.
Review in Experimental lung research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Role of regulatory T cells in mouse lung development.Experimental biology and medicine (Maywood, N.J.) · 2024Article
- Premature infants born <28 weeks with acute kidney injury have increased bronchopulmonary dysplasia rates.Pediatric research · 2023Article
- Neonatal hyperoxia induces activated pulmonary cellular states and sex-dependent transcriptomic changes in a model of experimental bronchopulmonary dysplasia.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- Perinatal Inflammatory Biomarkers and Respiratory Disease in Preterm Infants.The Journal of pediatrics · 2022Article
- Patho-mechanisms of the origins of bronchopulmonary dysplasia.Molecular and cellular pediatrics · 2021Review
- FOSL1 is a novel mediator of endotoxin/lipopolysaccharide-induced pulmonary angiogenic signaling.Scientific reports · 2020Article
- Advancements in understanding the role of lysophospholipids and their receptors in lung disorders including bronchopulmonary dysplasia.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020Review
- Vascular Niche in Lung Alveolar Development, Homeostasis, and Regeneration.Frontiers in bioengineering and biotechnology · 2019Review
- Effects and molecular mechanisms of intrauterine infection/inflammation on lung development.Respiratory research · 2018Article
- Effects of thalidomide on growth and VEGF-A expression in SW480 colon cancer cells.Oncology letters · 2018Article
- A Pathogenic Relationship of Bronchopulmonary Dysplasia and Retinopathy of Prematurity? A Review of Angiogenic Mediators in Both Diseases.Frontiers in pediatrics · 2018Review
- The BPD trio? Interaction of dysregulated PDGF, VEGF, and TGF signaling in neonatal chronic lung disease.Molecular and cellular pediatrics · 2017Review
- Article
- Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease.PloS one · 2016Article
- Deleted in malignant brain tumors 1 (DMBT1) elicits increased VEGF and decreased IL-6 production in type II lung epithelial cells.BMC pulmonary medicine · 2015Article
- Understanding the Impact of Infection, Inflammation, and Their Persistence in the Pathogenesis of Bronchopulmonary Dysplasia.Frontiers in medicine · 2015Review
- Animal models of bronchopulmonary dysplasia. The term mouse models.American journal of physiology. Lung cellular and molecular physiology · 2014Review
- Engineering de novo assembly of fetal pulmonary organoids.Tissue engineering. Part A · 2014Article
- Vascular mediators in chronic lung disease of infancy: role of endothelial monocyte activating polypeptide II (EMAP II).Birth defects research. Part A, Clinical and molecular teratology · 2014Review
- Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia.Birth defects research. Part A, Clinical and molecular teratology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD) contribute significantly to neonatal morbidity and mortality. Pulmonary function depends on the interaction between alveolar microvasculature and airspace development. While it has been shown in various animal models that vascular endothelial growth factor (VEGF) and its receptors increase in normal animal lung development, its pathophysiological role in neonatal respiratory failure is not yet entirely clear. Current animal and human studies exhibit controversial results. Though animal models are invaluable tools in the study of human lung disease, inherent differences in physiology mandate clarification of the timing of these studies to ensure that they appropriately correlate with the human stages of lung development. The purpose of this review article is to highlight the importance of considering the temporal relationship of VEGF and lung development in human neonates and developmentally-appropriate animal models with RDS and BPD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.