ArticlePloS one2012
Caenorhabditis elegans maintains highly compartmentalized cellular distribution of metals and steep concentration gradients of manganese.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 49 citations in OpenAlex.
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- Development of Multi-Scale X-ray Fluorescence Tomography for Examination of Nanocomposite-Treated Biological Samples.Cancers · 2021Article
- A new triazine bearing a pyrazolone group capable of copper, nickel, and zinc chelation.RSC advances · 2018Article
- Profiling changes to natively-bound metals duringRSC advances · 2016Article
- Elemental mapping of the entire intact Drosophila gastrointestinal tract.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2015Article
- Elemental bioimaging of Cisplatin in Caenorhabditis elegans by LA-ICP-MS.Metallomics : integrated biometal science · 2015Article
- DirectChemical science · 2015Article
- Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans.Metallomics : integrated biometal science · 2014Article
- Elemental and chemically specific X-ray fluorescence imaging of biological systems.Chemical reviews · 2014Review
- X-ray nanoprobes and diffraction-limited storage rings: opportunities and challenges of fluorescence tomography of biological specimens.Journal of synchrotron radiation · 2014Article
- 3D imaging of transition metals in the zebrafish embryo by X-ray fluorescence microtomography.Metallomics : integrated biometal science · 2014Article
- X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder.Chemical science · 2014Article
- Elemental bioimaging of manganese uptake in C. elegans.Metallomics : integrated biometal science · 2014Article
- Experimental demonstration of novel imaging geometries for x-ray fluorescence computed tomography.Medical physics · 2013Article
- Tertiary structure-based analysis of microRNA-target interactions.RNA (New York, N.Y.) · 2013Article
- Article
- Metal-induced neurodegeneration in C. elegans.Frontiers in aging neuroscience · 2013Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioinorganic chemistry is critical to cellular function. Homeostasis of manganese (Mn), for example, is essential for life. A lack of methods for direct in situ visualization of Mn and other biological metals within intact multicellular eukaryotes limits our understanding of management of these metals. We provide the first quantitative subcellular visualization of endogenous Mn concentrations (spanning two orders of magnitude) associated with individual cells of the nematode, Caenorhabditis elegans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.