ArticleJournal of clinical medicine research2011
Short-term effects of high-frequency chest compression and positive expiratory pressure in patients with cystic fibrosis.
Article in Journal of clinical medicine research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 6 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Airway clearance techniques compared to no airway clearance techniques for cystic fibrosis.The Cochrane database of systematic reviews · 2023Pooled it
- Oscillating devices for airway clearance in people with cystic fibrosis.The Cochrane database of systematic reviews · 2020Pooled it
- Positive expiratory pressure physiotherapy for airway clearance in people with cystic fibrosis.The Cochrane database of systematic reviews · 2019Pooled it
- Oscillating devices for airway clearance in people with cystic fibrosis.The Cochrane database of systematic reviews · 2017Pooled it
- Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis.The Cochrane database of systematic reviews · 2015Pooled it
- Effectiveness of positive expiratory pressure on patients over 16 years of age with cystic fibrosis: systematic review and meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Safety and effectiveness of the high-frequency chest wall oscillation vs intrapulmonary percussive ventilation in patients with severe COPD.International journal of chronic obstructive pulmonary disease · 2018Trial
- Effectiveness of treatment with high-frequency chest wall oscillation in patients with bronchiectasis.BMC pulmonary medicine · 2013Trial
- Airway Colonization in Children with Medical Complexity: Challenges and Management Strategies.Journal of clinical medicine · 2025Review
- A pilot study for development of a pulmonary function test induction jacket to automate effort in performing the forced vital capacity manoeuvre.Scientific reports · 2023Article
- Methods Used to Evaluate the Immediate Effects of Airway Clearance Techniques in Adults with Cystic Fibrosis: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2021Review
- Article
- Structure and function of the mucus clearance system of the lung.Cold Spring Harbor perspectives in medicine · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystic fibrosis patients require daily airway clearance therapies. The primary objective of this study was to compare the short-term efficacy of high-frequency chest compression and positive expiratory pressure mask on expectorated sputum, pulmonary function, and oxygen saturation in patients with CF hospitalized for an acute pulmonary exacerbation.
methodsA controlled randomized cross-over trial with 24 hours between treatments was used. Thirty-four CF patients (26 ± 6.5 years) were included in the study. Before and 30 minutes after each treatment were recorded: pulmonary function testing, oxygen saturation, and perceived dyspnea. Preference for the two devices was assessed.
resultsNo statistically significant difference between high-frequency chest compression and positive expiratory pressure mask was found in sputum production and in lung function testing. A reduction in SpO(2) was found after positive expiratory pressure mask (98 ± 1.0% versus 97 ± 1.2%; P < 0.001). Both treatments induced a statistically significant increase in Borg scale for dyspnea without differences between them. Patients reported greater satisfaction with positive expiratory pressure mask than with high-frequency chest compression (P < 0.001).
conclusionHigh-frequency chest compression and positive expiratory pressure mask have comparable short-term effects on expectorated sputum and lung function. Although positive expiratory pressure mask was associated with a lower SpO(2), it was better tolerated than high-frequency chest compression. KEYWORDS: Airway clearance therapies; High-frequency chest compression; Sputum; Cystic fibrosis.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.