ArticleSmall (Weinheim an der Bergstrasse, Germany)2012
Probing Access Resistance of Solid-state Nanopores with a Scanning Probe Microscope Tip.
Article in Small (Weinheim an der Bergstrasse, Germany), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Phyto-assisted eco-benevolent synthesis of oxidase-mimic Cu-MnBioprocess and biosystems engineering · 2025Article
- Effective Modulation of Ion Mobility through Solid-State Single-Digit Nanopores.Nanomaterials (Basel, Switzerland) · 2022Article
- Electric control of ionic transport in sub-nm nanopores.RSC advances · 2021Article
- EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX.Nature microbiology · 2018Article
- Dynamics of a Molecular Plug Docked onto a Solid-State Nanopore.The journal of physical chemistry letters · 2018Article
- DNA origami scaffold for studying intrinsically disordered proteins of the nuclear pore complex.Nature communications · 2018Article
- Article
- A tip-attached tuning fork sensor for the control of DNA translocation through a nanopore.The Review of scientific instruments · 2017Article
- Dielectrophoretic stretching of DNA tethered to a fiber tip.Nanotechnology · 2015Article
- Characterization of protein unfolding with solid-state nanopores.Protein and peptide letters · 2014Review
- Effect of Nanopore Length on the Translocation Process of a Biopolymer: Numerical Study.Materials (Basel, Switzerland) · 2013Article
- Recent trends in nanopores for biotechnology.Current opinion in biotechnology · 2013Review
- Threading immobilized DNA molecules through a solid-state nanopore at >100 μs per base rate.ACS nano · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
An apparatus that integrates solid-state nanopore ionic current measurement with a Scanning Probe Microscope has been developed. When a micrometer-scale scanning probe tip is near a voltage biased nanometer-scale pore (10-100 nm), the tip partially blocks the flow of ions to the pore and increases the pore access resistance. The apparatus records the current blockage caused by the probe tip and the location of the tip simultaneously. By measuring the current blockage map near a nanopore as a function of the tip position in 3D space in salt solution, we estimate the relative pore resistance increase due to the tip, ΔR/R(0), as a function of the tip location, nanopore geometry, and salt concentration. The amplitude of ΔR/R(0) also depends on the ratio of the pore length to its radius as Ohm's law predicts. When the tip is very close to the pore surface, ~10 nm, our experiments show that ΔR/R(0) depends on salt concentration as predicted by the Poisson and Nernst-Planck equations. Furthermore, our measurements show that ΔR/R(0) goes to zero when the tip is about five times the pore diameter away from the center of the pore entrance. The results in this work not only demonstrate a way to probe the access resistance of nanopores experimentally, they also provide a way to locate the nanopore in salt solution, and open the door to future nanopore experiments for detecting single biomolecules attached to a probe tip.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.