Evidence map›Paper›PMID 22393278›Full record

ArticleMolecular vision2012

Lack of association between IL10 polymorphisms and sarcoidosis in Japanese patients.

Kenichi Sakuyama, Akira Meguro, Masao Ota, Mami Ishihara, Riyo Uemoto, Haruyasu Ito, Eiichi Okada, Kenichi Namba, Nobuyoshi Kitaichi, Shin-ichiro Morimoto and 7 more

Open access · greenAbstract read
In one paragraph

Article in Molecular vision, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Kenichi SakuyamaDepartment of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan. ken136a@yahoo.co.jp
Akira Meguro
Masao Ota
Mami Ishihara
Riyo Uemoto
Haruyasu Ito
Eiichi Okada
Kenichi Namba
Nobuyoshi Kitaichi
Shin-ichiro Morimoto
Toshikatsu Kaburaki
Yasutaka Ando
Shinobu Takenaka
Takenosuke Yuasa
Shigeaki Ohno
Hidetoshi Inoko
Nobuhisa Mizuki
Yokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether interleukin 10 (IL10) gene polymorphisms are associated with the development of sarcoidosis in Japanese patients.

methodsTwo hundred and eighty-eight Japanese sarcoidosis patients and 310 Japanese healthy controls were recruited. We genotyped 9 single-nucleotide polymorphisms in IL10 and assessed the allelic diversity between cases and controls.

resultsNo significant differences in the frequency of IL10 alleles, genotypes, and haplotypes in the sarcoidosis cases compared to the controls were detected.

conclusionsOur results suggest that IL10 polymorphisms are not significantly related to the pathogenesis of sarcoidosis in the Japanese population.

Indexed as

Asian People5' Untranslated RegionsAllelesCase-Control StudiesDNA FingerprintingEyeGene FrequencyGenotypeHumansInterleukin-10IntronsLinkage DisequilibriumPolymorphism, Single NucleotideSarcoidosis5' Untranslated RegionsIL10 protein, humanInterleukin-10

Identifiers

PMID22393278
PMCPMC3291520
OpenAlexW1585656118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.