Evidence map›Paper›PMID 22393036›Full record

GuidelineAnnals of internal medicine2012

Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: evidence-based recommendations from an International Association of Physicians in AIDS Care panel.

Melanie A Thompson, Michael J Mugavero, K Rivet Amico, Victoria A Cargill, Larry W Chang, Robert Gross, Catherine Orrell, Frederick L Altice, David R Bangsberg, John G Bartlett and 10 more

Registry-linked trialOpen access · greenAbstract readPractice Guideline
In one paragraph

Guideline in Annals of internal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02459678 (ART Readiness in HIV-infected Pregnant Women), which is not on this map. Cited by 369 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
369citing papers in PubMed, 13 pooled it
39.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02459678 nacompletednot on this mapstarted 2015, after this paper: background citation

ART Readiness in HIV-infected Pregnant Women: From Formative Qualitative Research to Individual Randomized Trial

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2015 to 2018Enrolled454ConditionsHuman Immunodeficiency VirusArmsEnhanced Adherence Package, Standard of Care
3 · Its place in the literature

Who cites it

369 citing papers in PubMed, 13 syntheses or guidelines pooled it, 595 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Treatment of Drug-Resistant Tuberculosis. An Official ATS/CDC/ERS/IDSA Clinical Practice Guideline.American journal of respiratory and critical care medicine · 2019
    Guideline
  4. Pooled it
  5. Pooled it
  6. Antiretroviral resistance testing in HIV-positive people.The Cochrane database of systematic reviews · 2018
    Pooled it
  7. Guideline
  8. Mental health and retention in HIV care: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
    Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Guideline
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
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  20. Trial

309 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Melanie A ThompsonAIDS Research Consortium of Atlanta, Atlanta, GA 30308, USA.
Michael J Mugavero
K Rivet Amico
Victoria A Cargill
Larry W Chang
Robert Gross
Catherine Orrell
Frederick L Altice
David R Bangsberg
John G Bartlett
Curt G Beckwith
Nadia Dowshen
Christopher M Gordon
Tim Horn
Princy Kumar
James D Scott
Michael J Stirratt
Robert H Remien
Jane M Simoni
Jean B Nachega
Office of AIDS Research · USColumbia University · USGeorgetown University · USJohns Hopkins University · USNational Institutes of Health · USUniversity of Cape Town · ZA

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
Peer health workers: Impact on retention, care and secondary prevention of PLHIVK23MH086338 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CHANG, LARRY WILLIAM · 2010 to 2014
$914k
Comprehensive HIV Testing Strategies for JailsK23DA021095 · NIDA · MIRIAM HOSPITAL · PI BECKWITH, CURT G · 2007 to 2011
$779k
Mentoring Diverse Scientists in Global HIV Research on Mental Health & AdherenceK24MH093243 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2011 to 2014
$590k
NIAID NIH HHS P30 AI027757NIAID NIH HHS P30 AI042853NIDA NIH HHS K23 DA021095NIMH NIH HHS K23 MH086338NIMH NIH HHS K24 MH093243NIMH NIH HHS P30 MH043520
6 · The paper itself

Abstract

descriptionAfter HIV diagnosis, timely entry into HIV medical care and retention in that care are essential to the provision of effective antiretroviral therapy (ART). Adherence to ART is among the key determinants of successful HIV treatment outcome and is essential to minimize the emergence of drug resistance. The International Association of Physicians in AIDS Care convened a panel to develop evidence-based recommendations to optimize entry into and retention in care and ART adherence for people with HIV.

methodsA systematic literature search was conducted to produce an evidence base restricted to randomized, controlled trials and observational studies with comparators that had at least 1 measured biological or behavioral end point. A total of 325 studies met the criteria. Two reviewers independently extracted and coded data from each study using a standardized data extraction form. Panel members drafted recommendations based on the body of evidence for each method or intervention and then graded the overall quality of the body of evidence and the strength for each recommendation. RECOMMENDATIONS: Recommendations are provided for monitoring entry into and retention in care, interventions to improve entry and retention, and monitoring of and interventions to improve ART adherence. Recommendations cover ART strategies, adherence tools, education and counseling, and health system and service delivery interventions. In addition, they cover specific issues pertaining to pregnant women, incarcerated individuals, homeless and marginally housed individuals, and children and adolescents, as well as substance use and mental health disorders. Recommendations for future research in all areas are also provided.

Indexed as

Medication AdherenceAnti-HIV AgentsBiomedical ResearchCase ManagementCounselingDelivery of Health CareEvidence-Based MedicineFemaleHIV InfectionsHumansMonitoring, PhysiologicPatient Education as TopicPregnancyRandomized Controlled Trials as TopicReminder SystemsAnti-HIV Agents

Identifiers

PMID22393036
PMCPMC4044043
OpenAlexW2108276595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.