Evidence map›Paper›PMID 22392949›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2012

Accuracy of single-pass whole-body computed tomography for detection of injuries in patients with major blunt trauma.

Dirk Stengel, Caspar Ottersbach, Gerrit Matthes, Moritz Weigeldt, Simon Grundei, Grit Rademacher, Anja Tittel, Sven Mutze, Axel Ekkernkamp, Matthias Frank and 2 more

Open access · goldAbstract read
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 82 citations in OpenAlex.

  1. Imaging strategies for patients with multiple and/or severe injuries in the resuscitation room: a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Pooled it
  2. Pooled it
  3. Indications for total-body computed tomography in blunt trauma patients: a systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2017
    Pooled it
  4. Emergency ultrasound-based algorithms for diagnosing blunt abdominal trauma.The Cochrane database of systematic reviews · 2015
    Pooled it
  5. Trial
  6. Review
  7. Identifying Transfusion Triggers in Trauma Patients and Developing the Vellore Trauma Transfusion Score: A Retrospective Cohort Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  8. Observational
  9. Article
  10. Article
  11. Influencing factors for delayed diagnosed injuries in multiple trauma patients - introducing the 'Risk for Delayed Diagnoses Score' (RIDD-Score).European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Assessment of sensitivity of whole body CT for major trauma.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2019
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Dirk StengelCentre for Clinical Research, Unfall krankenhaus Berlin, Berlin, Germany. dirk.stengel@ukb.de
Caspar Ottersbach
Gerrit Matthes
Moritz Weigeldt
Simon Grundei
Grit Rademacher
Anja Tittel
Sven Mutze
Axel Ekkernkamp
Matthias Frank
Uli Schmucker
Julia Seifert
Unfallkrankenhaus Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContrast-enhanced whole-body computed tomography (also called "pan-scanning") is considered to be a conclusive diagnostic tool for major trauma. We sought to determine the accuracy of this method, focusing on the reliability of negative results.

methodsBetween July 2006 and December 2008, a total of 982 patients with suspected severe injuries underwent single-pass pan-scanning at a metropolitan trauma centre. The findings of the scan were independently evaluated by two reviewers who analyzed the injuries to five body regions and compared the results to a synopsis of hospital charts, subsequent imaging and interventional procedures. We calculated the sensitivity and specificity of the pan-scan for each body region, and we assessed the residual risk of missed injuries that required surgery or critical care.

resultsA total of 1756 injuries were detected in the 982 patients scanned. Of these, 360 patients had an Injury Severity Score greater than 15. The median length of follow-up was 39 (interquartile range 7-490) days, and 474 patients underwent a definitive reference test. The sensitivity of the initial pan-scan was 84.6% for head and neck injuries, 79.6% for facial injuries, 86.7% for thoracic injuries, 85.7% for abdominal injuries and 86.2% for pelvic injuries. Specificity was 98.9% for head and neck injuries, 99.1% for facial injuries, 98.9% for thoracic injuries, 97.5% for abdominal injuries and 99.8% for pelvic injuries. In total, 62 patients had 70 missed injuries, indicating a residual risk of 6.3% (95% confidence interval 4.9%-8.0%).

interpretationWe found that the positive results of trauma pan-scans are conclusive but negative results require subsequent confirmation. The pan-scan algorithms reduce, but do not eliminate, the risk of missed injuries, and they should not replace close monitoring and clinical follow-up of patients with major trauma.

Indexed as

Tomography, X-Ray ComputedWhole Body ImagingAdultFemaleHumansMaleSensitivity and SpecificityTrauma CentersWounds, Nonpenetrating

Identifiers

PMID22392949
PMCPMC3348190
OpenAlexW2075256321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.