Evidence map›Paper›PMID 22392766›Full record

ArticleArthritis care & research2012

Decision tool to improve the quality of care in rheumatoid arthritis.

Liana Fraenkel, Ellen Peters, Peter Charpentier, Blair Olsen, Lanette Errante, Robert T Schoen, Valerie Reyna

Abstract read
In one paragraph

Article in Arthritis care & research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Comparison of the Effects of a Pharmaceutical Industry Decision Guide and Decision Aids on Patient Choice to Intensify Therapy in Rheumatoid Arthritis.Medical decision making : an international journal of the Society for Medical Decision Making · 2017
    Trial
  7. Trial
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  9. Trial
  10. Article
  11. Observational
  12. Review
  13. Article
  14. Supporting Health and Medical Decision Making: Findings and Insights from Fuzzy-Trace Theory.Medical decision making : an international journal of the Society for Medical Decision Making · 2022
    Article
  15. Article
  16. Development of an App to Facilitate Communication and Shared Decision-making With Parents of Febrile Infants ≤ 60 Days Old.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2021
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liana FraenkelYale University School of Medicine, Section of Rheumatology, 300 Cedar Street, TAC#525, PO Box 208031, New Haven, CT 06520-8031, USA. liana.fraenkel@yale.edu
Ellen Peters
Peter Charpentier
Blair Olsen
Lanette Errante
Robert T Schoen
Valerie Reyna

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Improving Decision Making in Patients with Rheumatic DiseaseK24AR060231 · NIAMS · YALE UNIVERSITY · PI FRAENKEL, LIANA · 2011 to 2018
$1.2M
Low-Burden Tools for Improving Prediction and Diagnosis of Cognitive Impairment.RC1AG036915 · NIA · CORNELL UNIVERSITY · PI BRAINERD, CHARLES J, REYNA, VALERIE FRANCES · 2009 to 2010
$757k
NIAMS NIH HHS K24 AR060231NIA NIH HHS P30 AG021342NIA NIH HHS P30AG021342NIA NIH HHS RC1 AG036915NIA NIH HHS RC1AG036915-01
6 · The paper itself

Abstract

objectiveDespite the importance of achieving tight control, many patients with rheumatoid arthritis (RA) are not effectively treated with disease-modifying antirheumatic drugs. The objective of this study was to develop a decision support tool to inform RA patients with ongoing active disease about the risks and benefits related to biologic therapy.

methodsWe developed a balanced, web-based, decision support tool. Options, values, and probabilistic information were described using theoretically supported formulations. We conducted a pre-/posttest study to assess preliminary evidence of the tool's efficacy in improving knowledge related to biologics, clarity of values, willingness to take a biologic, and informed choice.

resultsWe interviewed 104 subjects (mean age 62 years, 84% women, 87% white, and median duration of RA 8 years). Knowledge (coded on a 0-20 scale) and willingness to take a biologic (coded on a 0-10 scale) significantly increased after viewing the tool (mean differences 2.3 and 1.4, respectively; P < 0.0001 for both). Perceived knowledge and values clarity (coded on 0-100 scales) also significantly improved (mean differences 20.4 and 20.8, respectively; P < 0.0001 for both). The proportion of subjects making an informed value-concordant choice increased substantially from 35% to 64%.

conclusionA tool designed to effectively communicate the risks and benefits associated with biologic therapy increased knowledge, patient willingness to escalate care, and the likelihood of making an informed choice. The results of this study support the need for a clinical trial to examine the impact of the tool in clinical practice.

Indexed as

Decision Making, Computer-AssistedPatient ParticipationQuality of Health CareAgedAntirheumatic AgentsArthritis, RheumatoidChoice BehaviorFemaleHumansMaleMiddle AgedPhysician-Patient RelationsRisk FactorsSurveys and QuestionnairesTreatment OutcomeAntirheumatic Agents

Identifiers

PMID22392766
PMCPMC3375390

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.