Evidence map›Paper›PMID 22392241›Full record

ArticleBrazilian journal of otorhinolaryngology2012

Antimicrobial activity of Terminalia arjuna Wight & Arn.: an ethnomedicinal plant against pathogens causing ear infection.

Kamal Rai Aneja, Chetan Sharma, Radhika Joshi

Open access · goldAbstract read
In one paragraph

Article in Brazilian journal of otorhinolaryngology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
  2. Bioassay-guided isolation of antibacterial compounds from the leaf extract of Terminalia Arjuna against the Vibrio species in shrimp.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Plants of the GenusFrontiers in pharmacology · 2020
    Review
  10. Endophytic Fungi fromJournal of fungi (Basel, Switzerland) · 2019
    Review
  11. A Comprehensive Review of the Structure Elucidation of Tannins fromEvidence-based complementary and alternative medicine : eCAM · 2019
    Review
  12. Article
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  14. Evaluation ofBiotechnology reports (Amsterdam, Netherlands) · 2017
    Article
  15. Medicinal properties ofJournal of traditional and complementary medicine · 2017
    Review
  16. Article
  17. Review
  18. Journal of advanced pharmaceutical technology & research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kamal Rai AnejaDepartment of Microbiology, Kurukshetra University, 136119 Kurukshetra, Haryana, India.
Chetan Sharma
Radhika Joshi
Kurukshetra University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledEar infection is one of the common diseases occurring throughout the world. Different etiological agents are responsible for ear infections.

aimTo assess the antimicrobial potential of Terminalia arjuna leaves and bark extracts against Staphylococcus aureus, Acinetobacter sp., Proteus mirabilis, Escherchia coli, Pseudomonas aeruginosa and Candida albicans, pathogens causing ear infections and their comparison with locally available ear drops. MATERIALS AND

methodsMethanol, ethanol, acetone, aqueous (hot and cold) extracts from the leaves and bark of T. arjuna were tested for their antimicrobial activity.

resultsOf the three organic solvents evaluated, acetonic leaf extract was found to be best against S. aureus. Organic bark extract showed almost equal inhibition of all tested Gram negative bacteria except P. aeruginosa. However, aqueous extract of T. arjuna bark exhibited good activity against S. aureus. All the extracts were unable to exhibit any antifungal activity.

conclusionOrganic extract obtained from the T. arjuna bark and leaves may be used to treat the bacterial ear pathogens especially S. aureus, which has shown greater inhibition zones than the herbal drops, however, we still need more detailed studies as in vivo testing and pharmacokinetics properties for their therapeutic utility in treating ear infections.

Indexed as

Anti-Infective AgentsCandida albicansGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsMolecular Sequence DataOtitisPlant ExtractsTerminaliaAnti-Infective AgentsPlant Extracts

Identifiers

PMID22392241
PMCPMC9444551
OpenAlexW2119801209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.