ReviewNature reviews. Clinical oncology2012
Exercise rehabilitation in patients with cancer.
Review in Nature reviews. Clinical oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01843608 (Effect of Combined Training Post-treatment Intervention in Lean Body Mass Recovery in Breast Cancer Survival. A Randomised Controlled Trial.), which is not on this map. Cited by 78 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Combined Training Post-treatment Intervention in Lean Body Mass Recovery in Breast Cancer Survival. A Randomised Controlled Trial.
Who cites it
78 citing papers in PubMed, 5 syntheses or guidelines pooled it, 163 citations in OpenAlex.
- Comparative Efficacy of Different Exercise Therapies for Cardiorespiratory Fitness in Breast Cancer Survivors: A Systematic Review and Bayesian Network Meta-analysis.Sports medicine - open · 2025Pooled it
- Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable.Medicine and science in sports and exercise · 2019Guideline
- Exercise training for advanced lung cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Lifestyle factors and health-related quality of life in bladder cancer survivors: a systematic review.Journal of cancer survivorship : research and practice · 2016Pooled it
- Survivorship: healthy lifestyles, version 2.2014.Journal of the National Comprehensive Cancer Network : JNCCN · 2014Guideline
- Increasing physical activity in Cancer Survivors through a Text-messaging Exercise motivation Program (ICanSTEP).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Trial
- Muscle strength in breast cancer patients receiving different treatment regimes.Journal of cachexia, sarcopenia and muscle · 2017Trial
- POSITIVE study: physical exercise program in non-operable lung cancer patients undergoing palliative treatment.BMC cancer · 2016Trial
- The influence of high-intensity compared with moderate-intensity exercise training on cardiorespiratory fitness and body composition in colorectal cancer survivors: a randomised controlled trial.Journal of cancer survivorship : research and practice · 2016Trial
- Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations.Journal of cancer survivorship : research and practice · 2015Trial
- Trial
- Trial
- Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy.BMC cancer · 2015Trial
- Supervised physical exercise to improve the quality of life of cancer patients: the EFICANCER randomised controlled trial.BMC cancer · 2015Trial
- Efficacy of multimodal exercise-based rehabilitation on physical activity, cardiorespiratory fitness, and patient-reported outcomes in cancer survivors: a randomized, controlled trial.Annals of oncology : official journal of the European Society for Medical Oncology · 2013Trial
- A mixed exercise training programme is feasible and safe and may improve quality of life and muscle strength in multiple myeloma survivors.BMC cancer · 2013Trial
- Trial
- Microvascular skeletal muscle oxygenation and exercise capacity in childhood cancer survivors compared to healthy controls: a cross-sectional study.Scientific reports · 2025Article
- Handgrip strength assessment in breast cancer patients: validity and reliability of the Activ5 dynamometer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Emerging evidence indicates that patients with cancer have considerable impairments in cardiorespiratory fitness, which is likely to be a result of the direct toxic effects of anticancer therapy as well as the indirect consequences secondary to therapy (for example, deconditioning). This reduced cardiorespiratory fitness is associated with heightened symptoms, functional dependence, and possibly with an increased risk of cardiovascular morbidity and mortality. Current understanding of the complex interaction between the effects of the tumour and cancer-associated therapies on the organ components that govern cardiorespiratory fitness, and the effects of exercise training on these parameters is limited; further research will be critical for further progress of exercise-based rehabilitation in the oncology setting. We assess the current evidence regarding the level, mechanisms, and clinical importance of diminished cardiorespiratory fitness in patients with cancer. The efficacy and adaptations to exercise training to prevent and/or mitigate dysfunction in conjunction with exercise prescription considerations for clinical use are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.