Evidence map›Paper›PMID 22392001›Full record

Trial reportJournal of cardiovascular translational research2012

Economic methods in the century trial--a comprehensive lifestyle modification study for managing coronary artery disease.

James R Langabeer, Rigoberto Delgado, David Lairson, Nils P Johnson, K Lance Gould, Stefano M Sdringola

Abstract readClinical Trial, Phase IIIRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

James R LangabeerCenter for Emergency Research, University of Texas School of Public Health, 1200 Herman Pressler Street, RAS-W310, Houston, TX 77030, USA. James.R.Langabeer@uth.tmc.edu
Rigoberto Delgado
David Lairson
Nils P Johnson
K Lance Gould
Stefano M Sdringola
The University of Texas at Austin · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While most studies assess the cost-effectiveness of treating acute coronary conditions, the Century Health Study for Cardiovascular Medicine (Century Trial) focuses on ameliorating coronary artery disease (CAD) through a comprehensive lifestyle modification program. This 1,300-patient phase III randomized study uses positron emission tomography for risk stratification, complemented with comprehensive educational and motivational therapy for patients with preclinical or established CAD. The Century Trial is in its second year of a five-year follow-up protocol, and it is one of the first to combine imaging technology and lifestyle modification as a way to improve patient behavior and health. In this article, we present the economic study design used in the Century Trial and provide considerable methodological detail to serve as reference for other researchers. We describe the cost and effect estimation methods as well as our analysis and uncertainty modeling plans. The study will incorporate quality-adjusted life years and use a societal perspective to measure both in-trial and lifetime costs through incremental cost-effectiveness ratios. The approach we follow should provide further evidence on the cost-effectiveness of comprehensive lifestyle modification programs in regressing coronary artery disease.

Indexed as

Health Care CostsModels, EconomicResearch DesignRisk Reduction BehaviorCoronary Artery DiseaseCost-Benefit AnalysisHealth BehaviorHumansMarkov ChainsMotivationPatient Education as TopicPositron-Emission TomographyPredictive Value of TestsQuality-Adjusted Life YearsTreatment OutcomeUncertainty

Identifiers

PMID22392001
OpenAlexW2091789584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.