Evidence map›Paper›PMID 22391857›Full record

ArticleOrganic & biomolecular chemistry2012

A seminaphthofluorescein-based fluorescent chemodosimeter for the highly selective detection of cysteine.

Xiaofeng Yang, Yixing Guo, Robert M Strongin

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Detection of biological thiols based on a colorimetric method.Journal of Zhejiang University. Science. B
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaofeng YangDepartment of Chemistry, Portland State University, Portland, OR 97201, USA. xfyang@nwu.edu.cn
Yixing Guo
Robert M Strongin

Funding

Synthesis and Study of Novel Sensing AgentsR01EB002044 · NIBIB · PORTLAND STATE UNIVERSITY · PI STRONGIN, ROBERT M · 2003 to 2010
$1.6M
NIBIB NIH HHS R01 EB002044
6 · The paper itself

Abstract

A fluorescent chemodosimeter for cysteine detection was developed based on a tandem conjugate addition and intramolecular cyclization reaction. The method exhibited an excellent selectivity for cysteine over other biothiols such as homocysteine and glutathione.

Indexed as

CysteineFluoresceinsFluorescent DyesCysteineFluoresceinsFluorescent Dyesseminaphthofluorescein

Identifiers

PMID22391857
PMCPMC3386612

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.