ReviewCurrent opinion in allergy and clinical immunology2012
Influence of poverty and infection on asthma in Latin America.
Review in Current opinion in allergy and clinical immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Article
- Why has epidemiology not (yet) succeeded in identifying the origin of the asthma epidemic?International journal of epidemiology · 2023Article
- Asthmatic Symptoms in Children and Adolescents: the Role of Maternal Experiences of Racial Discrimination.Journal of racial and ethnic health disparities · 2022Article
- Slum decay in Sub-Saharan Africa: Context, environmental pollution challenges, and impact on dweller's health.Environmental epidemiology (Philadelphia, Pa.) · 2021Article
- Genetic polymorphisms in vitamin D pathway influence 25(OH)D levels and are associated with atopy and asthma.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020Article
- Soil-transmitted helminth parasites and allergy: Observations from Ecuador.Parasite immunology · 2019Review
- Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American population.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Article
- Social, Environmental and Behavioral Determinants of Asthma Symptoms in Brazilian Middle School Students-A National School Health Survey (Pense 2012).International journal of environmental research and public health · 2018Article
- Associations between infant fungal and bacterial dysbiosis and childhood atopic wheeze in a nonindustrialized setting.The Journal of allergy and clinical immunology · 2018Article
- Association of Serum Lipids and Obstructive Lung Disease in Hispanic/Latino Adults of Diverse Backgrounds.Journal of pulmonary & respiratory medicine · 2017Article
- Article
- The association of intrafamilial violence against children with symptoms of atopic and non-atopic asthma: A cross-sectional study in Salvador, Brazil.Child abuse & neglect · 2015Article
- Risk factors for acute asthma in tropical America: a case-control study in the City of Esmeraldas, Ecuador.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2015Article
- Asthma in Hispanics. An 8-year update.American journal of respiratory and critical care medicine · 2014Review
- Social determinants of childhood asthma symptoms: an ecological study in urban Latin America.Journal of community health · 2014Article
- Prevalence of asthma, rhinitis and eczema symptoms in rural and urban school-aged children from Oropeza Province - Bolivia: a cross-sectional study.BMC pulmonary medicine · 2014Article
- Food and nutrition insecurity: a marker of vulnerability to asthma symptoms.Public health nutrition · 2014Article
- Risk factors for non-atopic asthma/wheeze in children and adolescents: a systematic review.Emerging themes in epidemiology · 2014Review
- Association between environmental factors and current asthma, rhinoconjunctivitis and eczema symptoms in school-aged children from Oropeza Province--Bolivia: a cross-sectional study.Environmental health : a global access science source · 2013Article
- Environmental conditions, immunologic phenotypes, atopy, and asthma: new evidence of how the hygiene hypothesis operates in Latin America.The Journal of allergy and clinical immunology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
Abstract
purpose of reviewAsthma in Latin America is a growing public health problem and seems to be most prevalent and cause most morbidity among poor urban populations. This article will review the findings of recent human studies of the associations of asthma prevalence in Latin America with factors associated with poverty and inequality including childhood infections, stress, environment, nutrition and diet. RECENT
findingsMost asthma in childhood in Latin America is nonatopic and has been associated with exposures related to environmental dirt, diet and psychosocial distress. These factors are strongly linked to poverty and inequality. Interestingly, infections with bacterial, viral and parasitic pathogens in childhood appear to attenuate atopy in childhood but have no effect on asthma symptoms. There are biologically plausible mechanisms by which dirt exposures (e.g. endotoxin and other microbial products and nonmicrobial irritants), diet and obesity and psychosocial stress may cause airways inflammation. SUMMARY: Most childhood asthma in Latin America is nonatopic for which important risk factors are those of poverty including poor hygiene (i.e. dirt), poor diet and obesity and psychosocial stress. There is evidence that exposures to infections in early childhood reduce atopy but not asthma. Research is needed to identify causes of nonatopic asthma that may be suitable for primary prevention or other public health intervention strategies for asthma in Latin America.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.