Evidence map›Paper›PMID 22391552›Full record

ArticleAntimicrobial agents and chemotherapy2012

The composition of the culture medium influences the β-1,3-glucan metabolism of Aspergillus fumigatus and the antifungal activity of inhibitors of β-1,3-glucan synthesis.

Cécile Clavaud, Anne Beauvais, Lise Barbin, Hélène Munier-Lehmann, Jean-Paul Latgé

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Top five unanswered questions in fungal cell surface research.Cell surface (Amsterdam, Netherlands) · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. What Are the Functions of Chitin Deacetylases inFrontiers in cellular and infection microbiology · 2020
    Article
  11. Frontiers in immunology · 2020
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Role of Hydrophobins in Aspergillus fumigatus.Journal of fungi (Basel, Switzerland) · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cécile ClavaudUnité des Aspergillus and Unité de Chimie et Biocatalyse, Institut Pasteur, Paris, France.
Anne Beauvais
Lise Barbin
Hélène Munier-Lehmann
Jean-Paul Latgé
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vitro testing of Aspergillus fumigatus susceptibility to echinocandins has always been a challenge. Using a simple and quick colorimetric method to analyze the activity of inhibitors of β-1,3-glucan synthesis, we found that the composition of the culture medium significantly influences glucan synthesis and consequently the antifungal properties of inhibitors of β-1,3-glucan synthesis when they are tested alone or in combination with chitin synthase inhibitors.

Indexed as

Antifungal AgentsAspergillus fumigatusbeta-GlucansCaspofunginCulture MediaEchinocandinsGlycosidesLipopeptidesMiconazoleMicrobial Sensitivity TestsTriterpenesAntifungal Agentsbeta-1,3-glucanbeta-GlucansCaspofunginCulture MediaEchinocandinsenfumafunginGlycosidesLipopeptidesMiconazoleTriterpenes

Identifiers

PMID22391552
PMCPMC3370737
OpenAlexW2065346895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.