Evidence map›Paper›PMID 22389748›Full record

ArticleJournal of experimental stroke & translational medicine2009

Long-term survival and serial assessment of stroke damage and recovery - practical and methodological considerations.

Michel Modo

Abstract read
In one paragraph

Article in Journal of experimental stroke & translational medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Physical therapy exerts sub-additive and suppressive effects on intracerebral neural stem cell implantation in a rat model of stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michel ModoKing's College London, Institute of Psychiatry, Department of Neuroscience, London, UK.

Funding

Neuro-Vascular RegenerationP20EB007076 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI HIRSCHI, KAREN KEMPER · 2006 to 2009
$4.4M
Human Endothelial Cell DifferentiationR01HL096360 · NHLBI · YALE UNIVERSITY · PI HIRSCHI, KAREN KEMPER · 2009 to 2013
$1.5M
NHLBI NIH HHS R01 HL096360NIBIB NIH HHS P20 EB007076
6 · The paper itself

Abstract

Impairments caused by stroke remain the main cause for adult disability. Despite a vigorous research effort, only 1 thrombolytic treatment has been approved in acute stroke (<3h). The limitations of preclinical studies and how these can be overcome have been the subject of various guidelines. However, often these guidelines focus on the acute stroke setting and omit long-term outcome measures, such as behaviour and neuroimaging. The considerations and practicalities of including the serial assessment of these approaches and their significance to establish therapeutic efficacy are discussed here.

Identifiers

PMID22389748
PMCPMC3292406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.