ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2012
Understanding dementia prevalence among centenarians.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Review
- Cognitively healthy centenarians are genetically protected against Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Study of neuropathological changes and dementia in 100 centenarians in The 90+ Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Toxic Psychosocial Stress, Resiliency Resources and Time to Dementia Diagnosis in a Nationally Representative Sample of Older Americans in the Health and Retirement Study from 2006-2016.International journal of environmental research and public health · 2022Article
- Article
- Association of Cognitive Function Trajectories in Centenarians With Postmortem Neuropathology, Physical Health, and Other Risk Factors for Cognitive Decline.JAMA network open · 2021Article
- Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study.JAMA network open · 2020Observational
- Centenarians as Models of Resistance and Resilience to Alzheimer's Disease and Related Dementias.Advances in geriatric medicine and research · 2020Article
- Neuropsychological Test Performance of Cognitively Healthy Centenarians: Normative Data From the Dutch 100-Plus Study.Journal of the American Geriatrics Society · 2019Article
- Clinico-Neuropathological Findings in the Oldest Old from the Georgia Centenarian Study.Journal of Alzheimer's disease : JAD · 2019Article
- The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description.European journal of epidemiology · 2018Article
- Low carotid wall shear stress independently accelerates the progression of cognitive impairment and white matter lesions in the elderly.Oncotarget · 2018Article
- Factors Associated with Activities of Daily Life Disability among Centenarians in Rural Chongqing, China: A Cross-Sectional Study.International journal of environmental research and public health · 2017Article
- Article
- Excessive variability in systolic blood pressure that is self-measured at home exacerbates the progression of brain white matter lesions and cognitive impairment in the oldest old.Hypertension research : official journal of the Japanese Society of Hypertension · 2016Article
- Personality Structure Among Centenarians: The Georgia Centenarian Study.Experimental aging research · 2015Article
- Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease.Acta neuropathologica communications · 2014Review
- Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells.The journals of gerontology. Series A, Biological sciences and medical sciences · 2013Article
- Sources of variation on the mini-mental state examination in a population-based sample of centenarians.Journal of the American Geriatrics Society · 2013Article
- Dementia in the oldest old.Nature reviews. Neurology · 2013Review
Corrections and comments
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Authors and funding
12 authors at 9 institutions in 2 countries.
Funding
Abstract
The goals of this article are to (a) establish the concurrent and clinical validity of the Global Deterioration scale in assessing cognitive functions and stages of dementia among centenarians, (b) identify the prevalence of all-cause dementia in representative samples of centenarians, and (c) demonstrate how variations in sample demographic characteristics could significantly affect estimates of dementia prevalence. A quarter of the 244 centenarians in a population-based sample had no objective evidence of memory deficits. Another quarter showed signs of transient confusion, and about half showed classical behavioral signs of dementia with about 15% in each of Global Deterioration scale stages 4-6 and about 5% in the most severe stage 7. Variations in age, gender, race, residence status, and education of the study sample as well as criteria used for dementia rating were found to affect prevalence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.