ArticleApplied and environmental microbiology2012
Evidence of host-associated populations of Cryptosporidium parvum in Italy.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 67 citations in OpenAlex.
- Population structure and zoonotic potential of Cryptosporidium parvum in Italy inferred using a multi-locus sequence typing scheme.Parasites & vectors · 2026Article
- Molecular and Epidemiological Investigation ofPathogens (Basel, Switzerland) · 2025Article
- Design, development, and testing of a new multi-locus sequence typing scheme for the zoonotic pathogenCurrent research in parasitology & vector-borne diseases · 2025Article
- First identification of Cryptosporidium parvum virus 1 (CSpV1) in various subtypes of Cryptosporidium parvum from diarrheic calves, lambs and goat kids from France.Veterinary research · 2023Article
- Molecular Detection and Distribution ofTransboundary and emerging diseases · 2023Article
- Transmission of Cryptosporidium Species Among Human and Animal Local Contact Networks in Sub-Saharan Africa: A Multicountry Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Population structure and geographical segregation of Cryptosporidium parvum IId subtypes in cattle in China.Parasites & vectors · 2020Article
- Species and genotypes causing human cryptosporidiosis in New Zealand.Parasitology research · 2020Article
- Direct Sequencing ofFrontiers in public health · 2019Review
- Zoonotic Cryptosporidium species and subtypes in lambs and goat kids in Algeria.Parasites & vectors · 2018Article
- Sheep as a Potential Source of Zoonotic Cryptosporidiosis in China.Applied and environmental microbiology · 2018Article
- Evolutionary processes in populations of Cryptosporidium inferred from gp60 sequence data.Parasitology research · 2017Article
- Cryptosporidium genotypes in children and calves living at the wildlife or livestock interface of the Kruger National Park, South Africa.The Onderstepoort journal of veterinary research · 2016Article
- Molecular characterization of human Cryptosporidium spp. isolates after an unusual increase in late summer 2012.Parasites & vectors · 2016Article
- Intra-Species Diversity and Panmictic Structure of Cryptosporidium parvum Populations in Cattle Farms in Northern Spain.PloS one · 2016Article
- Article
- Emergence of novel subtypes of Cryptosporidium parvum in calves in Poland.Parasitology research · 2015Article
- Cryptosporidium species and subtype analysis in diarrhoeic pre-weaned lambs and goat kids from north-western Spain.Parasitology research · 2015Article
- Development of a framework for genotyping bovine-derived Cryptosporidium parvum, using a multilocus fragment typing tool.Parasites & vectors · 2015Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
Abstract
Recent studies have revealed extensive genetic variation among isolates of Cryptosporidium parvum, an Apicomplexan parasite that causes gastroenteritis in both humans and animals worldwide. The parasite's population structure is influenced by the intensity of transmission, the host-parasite interaction, and husbandry practices. As a result, C. parvum populations can be panmictic, clonal, or even epidemic on both a local scale and a larger geographical scale. To extend the study of C. parvum populations to an unexplored region, 173 isolates of C. parvum collected in Italy from humans and livestock (calf, sheep, and goat) over a 10-year period were genotyped using a multilocus scheme based on 7 mini- and microsatellite loci. In agreement with other studies, extensive polymorphism was observed, with 102 distinct multilocus genotypes (MLGs) identified among 173 isolates. The presence of linkage disequilibrium, the confinement of MLGs to individual farms, and the relationship of many MLGs inferred using network analysis (eBURST) suggest a predominantly clonal population structure, but there is also evidence that part of the diversity can be explained by genetic exchange. MLGs from goats were found to differ from bovine and sheep MLGs, supporting the existence of C. parvum subpopulations. Finally, MLGs from isolates collected between 1997 and 1999 were also identified as a distinct subgroup in principal-component analysis and eBURST analysis, suggesting a continuous introduction of novel genotypes in the parasite population.
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