Evidence map›Paper›PMID 22389165›Full record

ReviewAmerican journal of hematology2012

Cancer and coagulation.

Alok A Khorana

Open access · greenAbstract readReview
In one paragraph

Review in American journal of hematology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The secret enemy during a flight: Economy class syndrome.Anatolian journal of cardiology · 2021
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Prognostic Value of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Head and Neck Malignancies.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2020
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alok A KhoranaJames P Wilmot Cancer Center and the Department of Medicine, University of Rochester, Rochester, New York, USA. alok_khorana@urmc.rochester.edu
University of Rochester Medical Center · US

Funding

Venous Thrombosis in Cancer Outpatients: Prevention and Role of Tissue FactorR01HL095109 · NHLBI · UNIVERSITY OF ROCHESTER · PI FRANCIS, CHARLES W. · 2008 to 2012
$3.2M
Risk Factors for Venous Thromboembolism in Cancer Patients Receiving ChemotherapyK23CA120587 · NCI · UNIVERSITY OF ROCHESTER · PI KHORANA, ALOK A · 2006 to 2010
$649k
NCI NIH HHS K23 CA120587NHLBI NIH HHS R01 HL095109NHLBI NIH HHS R01HL095109
6 · The paper itself

Abstract

Thromboembolism, including both venous and arterial events, occurs commonly amongst patients with cancer. The occurrence of thromboembolism has significant consequences for cancer patients, including direct and indirect associations with mortality, morbidity, requirement for long-term anticoagulant therapy and consumption of healthcare resources. Recent studies have resulted in a better understanding of clinical risk factors and biomarkers of cancer-associated thrombosis, and a risk assessment model incorporating both has now been validated in multiple settings. Thromboprophylaxis with either unfractionated heparin or low-molecular-weight heparins (LMWHs) has been shown to be safe and effective in high-risk settings such as hospitalization for medical illness and the postsurgical period. Emerging new data from randomized studies have focused on outpatient prophylaxis, suggesting potential benefits in this setting as well. Treatment of cancer-associated thrombosis requires long-term anticoagulation with LMWH. Results from ongoing and planned trials of novel anticoagulants in the cancer setting are awaited.

Indexed as

Blood CoagulationAnticoagulantsBiomarkersHeparin, Low-Molecular-WeightHospitalizationHumansNeoplasmsRandomized Controlled Trials as TopicRisk FactorsThromboembolismAnticoagulantsBiomarkersHeparin, Low-Molecular-Weight

Identifiers

PMID22389165
PMCPMC3495606
OpenAlexW2091871712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.