ReviewDiabetes/metabolism research and reviews2012
Physical activity is related to insulin sensitivity in children and adolescents, independent of adiposity: a review of the literature.
Review in Diabetes/metabolism research and reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06770660 (Evaluating the Effectiveness of Telemedicine-based Exercise Programme in Improving Cardiorespiratory Fitness in Asian Paediatric Population), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluating the Effectiveness of Telemedicine-based Exercise Programme in Improving Cardiorespiratory Fitness in Asian Paediatric Population: a Randomised Controlled Trial
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- How to Teach Healthy Life-Style Efficiently in a Pediatric Outpatient Setting: Proposal of an Innovative Tridimensional Pyramid.Nutrients · 2026Pooled it
- Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis of randomized controlled studies.Frontiers in endocrinology · 2025Pooled it
- Prevention of insulin resistance in adolescents at risk for type 2 diabetes with depressive symptoms: 1-year follow-up of a randomized trial.Depression and anxiety · 2017Trial
- Physical Activity Patterns and Cardiometabolic Risk in Children and Adolescents with Obesity: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Acute Effects of Exercise on Metabolic, Inflammatory, and Immune Markers in Adolescent Girls with Normal Weight or Overweight/Obesity.Sports (Basel, Switzerland) · 2026Article
- Experiences of children with obesity and their parents of participating in a physical activity on prescription intervention: a qualitative study.Frontiers in pediatrics · 2026Article
- Reductive stress: The key pathway in metabolic disorders induced by overnutrition.Journal of advanced research · 2025Review
- The need for tailoring school-based physical activity interventions: preliminary insights into body weight and cross-country differences from the DELICIOUS project.Frontiers in public health · 2025Article
- Sleep duration and timing are prospectively linked with insulin resistance during late adolescence.Obesity (Silver Spring, Md.) · 2023Article
- Implementation of physical activity on prescription for children with obesity in paediatric health care (IMPA): protocol for a feasibility and evaluation study using quantitative and qualitative methods.Pilot and feasibility studies · 2022Article
- Waist Circumference Is Not Associated with Impaired Fasting Blood Glucose in a Sample of Mexican Children and Teenagers: Results from a State Screening Program.Children (Basel, Switzerland) · 2021Article
- Exercise and Insulin Resistance.Advances in experimental medicine and biology · 2020Review
- Insulin Sensitivity, Depression/Anxiety, and Physical Fitness in At-Risk Adolescents.Sports medicine international open · 2019Article
- Design of a randomized controlled trial to decrease depression and improve insulin sensitivity in adolescents: Mood and INsulin sensitivity to prevent Diabetes (MIND).Contemporary clinical trials · 2018Article
- An MG53-IRS1-interaction disruptor ameliorates insulin resistance.Experimental & molecular medicine · 2018Article
- Does cardiorespiratory fitness moderate the prospective association between physical activity and cardiometabolic risk factors in children?International journal of obesity (2005) · 2018Article
- Effect on the Metabolic Biomarkers in Schoolchildren After a Comprehensive Intervention Using Electronic Media and In-Person Sessions to Change Lifestyles: Community Trial.Journal of medical Internet research · 2018Article
- Physical Activity Throughout Adolescence and Hba1c in Early Adulthood: Birth Cohort Study.Journal of physical activity & health · 2017Article
- Update on the effects of physical activity on insulin sensitivity in humans.BMJ open sport & exercise medicine · 2016Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In adults, there is evidence that physical activity effectively improves insulin sensitivity regardless of adiposity. Whether this is also the case in children and adolescents is less clear. Clarifying this matter may help to identify the best outcomes to target in exercise programs for these age groups, where changes in adiposity may not always be desirable or realistic. A review of the literature was conducted on studies that examined the relationships of physical activity, cardiorespiratory fitness and strength with insulin sensitivity independent of adiposity in children and adolescents. Experimental (intervention) and correlational (longitudinal and cross-sectional) studies on participants ages 18 years and younger were identified. A total of 42 studies were included in this review. Sample sizes in the studies ranged from 14 to 4955 participants, with individual ages ranging from 5 to 19 years. A significant relationship with insulin sensitivity existed in 78% of studies on physical activity, 69% of studies on cardiorespiratory fitness and 66% of studies on strength. In studies that examined both physical activity and cardiorespiratory fitness concurrently, evidence suggests that they are both correlated with insulin sensitivity independent of adiposity, especially when physical activity is at higher intensities. However, the strength of this relationship might be influenced by study design, measurement techniques and participant characteristics. This is the first review of its type to take research design into account and to examine study outcomes according to participant ethnicity, gender, age, pubertal status and weight status.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.