Evidence map›Paper›PMID 22388630›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2012

Rationale for the use of radiolabelled peptides in diagnosis and therapy.

K P Koopmans, A W J M Glaudemans

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Anti-Cancer Peptides: Status and Future Prospects.Molecules (Basel, Switzerland) · 2023
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. 18F-Labeled Peptides: The Future Is Bright.Molecules (Basel, Switzerland) · 2014
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Radiolabelled peptides in diagnosis and therapy: an introduction.European journal of nuclear medicine and molecular imaging · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

K P KoopmansDepartment of Radiology and Nuclear Medicine, Martini Hospital, Van Swietenplein 1, 9728 NT Groningen, The Netherlands. k.koopmans@mzh.nl
A W J M Glaudemans

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear medicine techniques are becoming more important in imaging oncological and infectious diseases. For metabolic imaging of these diseases, antibody and peptide imaging are currently used. In recent years peptide imaging has become important, therefore the rationale for the use of peptide imaging is described in this article. Criteria for a successful peptide tracer are a high target specificity, a high binding affinity, a long metabolic stability and a high target-to-background ratio. Tracer internalization is also beneficial. For oncological imaging, many tracers are available, most originating from regulatory peptides, but penetrating peptides are also being developed. Peptides for imaging inflammatory and infectious diseases include regulatory peptides, antimicrobial peptides and others. In conclusion, for the imaging of oncological, imflammatory and infectious diseases, many promising peptides are being developed. The ideal peptide probe is characterized by rapid and specific target localization and binding with a high tumour-to-background ratio.

Indexed as

Antimicrobial Cationic PeptidesBombesinCholecystokininGastrin-Releasing PeptideGlucagon-Like Peptide 1HumansInfectionsInflammationIsotope LabelingNeoplasmsPeptidesRadionuclide ImagingRadiopharmaceuticalsSomatostatinVasoactive Intestinal PeptideAntimicrobial Cationic PeptidesBombesinCholecystokininGastrin-Releasing PeptideGlucagon-Like Peptide 1PeptidesRadiopharmaceuticalsSomatostatinVasoactive Intestinal Peptide

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.