Evidence map›Paper›PMID 22388627›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2012

Radiolabelled peptides for oncological diagnosis.

Peter Laverman, Jane K Sosabowski, Otto C Boerman, Wim J G Oyen

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 77 citations in OpenAlex.

  1. The novel [RSC advances · 2026
    Article
  2. CXCR4-targeted PET imaging of glioblastoma using [EJNMMI radiopharmacy and chemistry · 2026
    Article
  3. Article
  4. Article
  5. [International journal of molecular sciences · 2021
    Article
  6. Review
  7. Review
  8. Article
  9. PEGylated peptide to TIP1 is a novel targeting agent that binds specifically to various cancers in vivo.Journal of controlled release : official journal of the Controlled Release Society · 2019
    Article
  10. Article
  11. GPCR Modulation in Breast Cancer.International journal of molecular sciences · 2018
    Review
  12. Molecular biology reports · 2018
    Article
  13. Biodistribution and Internal Radiation Dosimetry ofCancer biotherapy & radiopharmaceuticals · 2018
    Article
  14. Article
  15. Imaging of Integrin αCancer biotherapy & radiopharmaceuticals · 2017
    Article
  16. Review
  17. Article
  18. Radiolabeled bombesin derivatives for preclinical oncological imaging.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2017
    Review
  19. Peptide-based imaging agents for cancer detection.Advanced drug delivery reviews · 2017
    Review
  20. Fully automated GMP production of [American journal of nuclear medicine and molecular imaging · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Peter LavermanDepartment of Nuclear Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. P.Laverman@nucmed.umcn.nl
Jane K Sosabowski
Otto C Boerman
Wim J G Oyen
Radboud University Nijmegen · NLQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiolabelled receptor-binding peptides targeting receptors (over)expressed on tumour cells are widely under investigation for tumour diagnosis and therapy. The concept of using radiolabelled receptor-binding peptides to target receptor-expressing tissues in vivo has stimulated a large body of research in nuclear medicine. The (111)In-labelled somatostatin analogue octreotide (OctreoScan) is the most successful radiopeptide for tumour imaging, and was the first to be approved for diagnostic use. Based on the success of these studies, other receptor-targeting peptides such as cholecystokinin/gastrin analogues, glucagon-like peptide-1, bombesin (BN), chemokine receptor CXCR4 targeting peptides, and RGD peptides are currently under development or undergoing clinical trials. In this review, we discuss some of these peptides and their analogues, with regard to their potential for radionuclide imaging of tumours.

Indexed as

PeptidesRadiopharmaceuticalsAnimalsBombesinCholecystokininGlucagon-Like Peptide 1Glucagon-Like Peptide-1 ReceptorHumansLigandsNeoplasmsOctreotidePentetic AcidRadionuclide ImagingReceptor, Cholecystokinin BReceptors, BombesinReceptors, CholecystokininBombesinCholecystokininCXCR4 protein, humanGLP1R protein, humanGlucagon-Like Peptide 1Glucagon-Like Peptide-1 ReceptorLigandsOctreotidePentetic AcidPeptidesRadiopharmaceuticalsReceptor, Cholecystokinin BReceptors, BombesinReceptors, CholecystokininReceptors, CXCR4Receptors, GlucagonSDZ 215-811

Identifiers

PMID22388627
PMCPMC3304069
OpenAlexW2030568152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.