Evidence map›Paper›PMID 22388575›Full record

ArticleJournal of feline medicine and surgery2012

Potassium iodide capsule treatment of feline sporotrichosis.

Erica G Reis, Isabella D F Gremião, Amanda A B Kitada, Raphael F D B Rocha, Verônica S P Castro, Mônica B L Barros, Rodrigo C Menezes, Sandro A Pereira, Tânia M P Schubach

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Journal of fungi (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. Journal of fungi (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Feline sporotrichosis: a case series of itraconazole-resistant Sporothrix brasiliensis infection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  10. Feline sporotrichosis in Asia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  11. Guideline for the management of feline sporotrichosis caused by Sporothrix brasiliensis and literature revision.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  12. A One Health Approach to CombattingJournal of fungi (Basel, Switzerland) · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Sporotrichosis in cats: ABCD guidelines on prevention and management.Journal of feline medicine and surgery · 2013
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Erica G ReisLaboratory of Clinical Research on Dermatozoonosis in Domestic Animals, Evandro Chagas Clinical Research Institute/Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. ericaguerino@gmail.com
Isabella D F Gremião
Amanda A B Kitada
Raphael F D B Rocha
Verônica S P Castro
Mônica B L Barros
Rodrigo C Menezes
Sandro A Pereira
Tânia M P Schubach
Fundação Oswaldo Cruz · BREscola Nacional de Saúde Pública · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sporotrichosis is a mycosis caused by Sporothrix schenckii. The most affected animal is the cat; it has played an important role in the zoonotic transmission of this disease, especially in Rio de Janeiro, Brazil, since 1998. In order to evaluate the treatment of feline sporotrichosis with potassium iodide, an observational cohort was conducted in 48 cats with sporotrichosis at Instituto de Pesquisa Clínica Evandro Chagas, Fiocruz. All cats received potassium iodide capsules, 2.5 mg/kg to 20 mg/kg q24h. The cure rate was 47.9%, treatment failure was 37.5%, treatment abandonment was 10.4% and death was 4.2%. Clinical adverse effects were observed in 52.1% of the cases. Thirteen cats had a mild increase in hepatic transaminase levels during the treatment, six of them presented clinical signs suggestive of hepatotoxicity. Compared to previous studies with itraconazole and iodide in saturated solution, potassium iodide capsules are an alternative for feline sporotrichosis treatment.

Indexed as

AnimalsAntifungal AgentsCapsulesCat DiseasesCatsDose-Response Relationship, DrugFemaleFollow-Up StudiesMalePotassium IodideSporotrichosisTreatment OutcomeAntifungal AgentsCapsulesPotassium Iodide

Identifiers

PMID22388575
PMCPMC10822585
OpenAlexW2021563364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.