ArticlePlant physiology2012
Synergistic biosynthesis of biphasic ethylene and reactive oxygen species in response to hemibiotrophic Phytophthora parasitica in tobacco plants.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 96 citations in OpenAlex.
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- The NbCBP1-NbSAMS1 Module Promotes Ethylene Accumulation to EnhanceInternational journal of molecular sciences · 2025Article
- ROS as Signaling Molecules to Initiate the Process of Plant Acclimatization to Abiotic Stress.International journal of molecular sciences · 2024Review
- The Role of Salicylic, Jasmonic Acid and Ethylene in the Development of the Resistance/Susceptibility of Wheat to the SnTox1-Producing Isolate of the Pathogenic FungusPlants (Basel, Switzerland) · 2024Article
- Functional genomics identifies a small secreted protein that plays a role during the biotrophic to necrotrophic shift in the root rot pathogenFrontiers in plant science · 2024Article
- Evaluation of Tunisian wheat endophytes as plant growth promoting bacteria and biological control agents against Fusarium culmorum.PloS one · 2024Article
- NPR1 Translocation from Chloroplast to Nucleus Activates Plant Tolerance to Salt Stress.Antioxidants (Basel, Switzerland) · 2023Article
- Engineering Resistance againstPlants (Basel, Switzerland) · 2022Article
- NtbHLH49, a jasmonate-regulated transcription factor, negatively regulates tobacco responses toFrontiers in plant science · 2022Article
- Molecular mechanisms of plant tolerance to heat stress: current landscape and future perspectives.Plant cell reports · 2021Review
- CRISPR/Cas9-MediatedInternational journal of molecular sciences · 2021Article
- Phytosphingosine induces systemic acquired resistance through activation of sphingosine kinase.Plant direct · 2021Article
- Perturbations in nitric oxide homeostasis promote Arabidopsis disease susceptibility towards Phytophthora parasitica.Molecular plant pathology · 2021Article
- Ethylene-Cytokinin Interaction Determines Early Defense Response of Wheat againstBiomolecules · 2021Article
- Homeobox transcription factor OsZHD2 promotes root meristem activity in rice by inducing ethylene biosynthesis.Journal of experimental botany · 2020Article
- Functional switching of NPR1 between chloroplast and nucleus for adaptive response to salt stress.Scientific reports · 2020Article
- GmWRKY40, a member of the WRKY transcription factor genes identified from Glycine max L., enhanced the resistance to Phytophthora sojae.BMC plant biology · 2019Article
- Synergistic Roles of Biphasic Ethylene and Hydrogen Peroxide in Wound-Induced Vessel Occlusions and Essential Oil Accumulation inFrontiers in plant science · 2019Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We observed the biphasic production of ethylene and reactive oxygen species (ROS) in susceptible tobacco (Nicotiana tabacum 'Wisconsin 38') plants after shoot inoculation with Phytophthora parasitica var nicotianae. The initial transient increase in ROS and ethylene at 1 and 3 h (phase I), respectively, was followed by a second massive increase at 48 and 72 h (phase II), respectively, after pathogen inoculation. This biphasic pattern of ROS production significantly differed from the hypersensitive response exhibited by cryptogein-treated wild-type tobacco plants. The biphasic increase in ROS production was mediated by both NADPH oxidase isoforms, respiratory burst oxidase homolog (Rboh) D and RbohF. Conversely, different 1-aminocyclopropane-1-carboxylic acid synthase members were involved in specific phases of ethylene production: NtACS4 in the first phase and NtACS1 in the second phase. Biphasic production of ROS was inhibited in transgenic antisense plant lines expressing 1-aminocyclopropane-1-carboxylic acid synthase/oxidase or ethylene-insensitive3 as well as in transgenic plants impaired in ROS production. All tested transgenic plants were more tolerant against P. parasitica var nicotianae infection as determined based on trypan blue staining and pathogen proliferation. Further, silencing of NtACS4 blocked the second massive increase in ROS production as well as pathogen progression. Pathogen tolerance was due to the inhibition of ROS and ethylene production, which further resulted in lower activation of ROS-detoxifying enzymes. Accordingly, the synergistic inhibition of the second phase of ROS and ethylene production had protective effects against pathogen-induced cell damage. We conclude that the levels of ethylene and ROS correlate with compatible P. parasitica proliferation in susceptible plants.
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