ArticleAnalytical biochemistry2012
On-the-resin N-terminal modification of long synthetic peptides.
Article in Analytical biochemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- Mono-ADP-Ribosylation of Peptides: An Overview of Synthetic and Chemoenzymatic Methodologies.Chembiochem : a European journal of chemical biology · 2024Review
- Versatile Click Linker Enabling Native Peptide Release from Nanocarriers upon Redox Trigger.Bioconjugate chemistry · 2023Article
- Synthetic Dual Cysteine-ADP Ribosylated Peptides from the Androgen Receptor are Recognized by the DTX3L/PARP9 Complex.ACS chemical biology · 2023Article
- Development of a Cyclic, Cell Penetrating Peptide Compatible with In Vitro Selection Strategies.ACS chemical biology · 2023Article
- Late-Stage Functionalisation of Peptides on the Solid Phase by an Iodination-Substitution Approach.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- EGFR-Binding Peptides: From Computational Design towards Tumor-Targeting of Adeno-Associated Virus Capsids.International journal of molecular sciences · 2020Article
- Multivalent, Soluble Nano-Self Peptides Increase Phagocytosis of Antibody-Opsonized Targets while Suppressing "Self" Signaling.ACS nano · 2020Article
- Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity.International journal of molecular sciences · 2020Article
- Fluorophores, environments, and quantification techniques in the analysis of transmembrane helix interaction using FRET.Biopolymers · 2015Review
- Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides.Macromolecular bioscience · 2015Article
- Imaging denatured collagen strands in vivo and ex vivo via photo-triggered hybridization of caged collagen mimetic peptides.Journal of visualized experiments : JoVE · 2014Article
- Targeting and mimicking collagens via triple helical peptide assembly.Current opinion in chemical biology · 2013Review
- The transmembrane domains of the bacterial cell division proteins FtsB and FtsL form a stable high-order oligomer.Biochemistry · 2013Article
- Direct detection of collagenous proteins by fluorescently labeled collagen mimetic peptides.Bioconjugate chemistry · 2013Article
- Targeting collagen strands by photo-triggered triple-helix hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Here we present a highly efficient protocol for on-the-resin coupling of fluorescent dyes or other functional groups to the N-termini of synthetic peptides prior to cleavage and deprotection. The protocol avoids expensive preactivated dyes and instead employs carboxylated dyes activated by large amounts of coupling reagents. The protocol was used to label peptides with low reactivity such as long hydrophobic peptides and peptides with strong tendencies to form sterically shielding structures or aggregates in solution. In all cases, the yields far exceeded those from commercially available preactivated compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.