ReviewThe Journal of allergy and clinical immunology2012
Asthma outcomes: composite scores of asthma control.
Review in The Journal of allergy and clinical immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 92 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
To Determine the Measurement Properties of the ACT in an Adolescent Population With Persistent Asthma Followed at a Subspecialty Clinic.
To Determine the Measurement Properties of the ACT in an African American Adolescent Population With Persistent Asthma Followed at a Subspecialty Clinic
Who cites it
92 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Control of Allergic Rhinitis and Asthma Test for Children (CARATkids): A systematic review and meta-analysis of its measurement properties.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Pooled it
- Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA).The European respiratory journal · 2023Pooled it
- Barriers and determinants of asthma control in children and adolescents in Africa: a systematic review.BMJ open · 2021Pooled it
- Pooled it
- Surrogate endpoints in liver surgery related trials: a systematic review of the literature.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2013Pooled it
- A Digital Asthma Self-Management Program for Adults: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Randomized trial of a portable HEPA air cleaner intervention to reduce asthma morbidity among Latino children in an agricultural community.Environmental health : a global access science source · 2022Trial
- Community Health Worker Asthma Interventions for Children: Results From a Clinically Integrated Randomized Comparative Effectiveness Trial (2016‒2019).American journal of public health · 2021Trial
- Fungal sensitization and its relationship to mepolizumab response in patients with severe eosinophilic asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2020Trial
- Impact of sleep opportunity on asthma outcomes in adolescents.Sleep medicine · 2020Trial
- Mepolizumab reduces exacerbations in patients with severe eosinophilic asthma, irrespective of body weight/body mass index: meta-analysis of MENSA and MUSCA.Respiratory research · 2019Trial
- Responsiveness of Single versus Composite Measures of Pain in Knee Osteoarthritis.The Journal of rheumatology · 2018Trial
- Design of a pragmatic trial in minority children presenting to the emergency department with uncontrolled asthma: The CHICAGO Plan.Contemporary clinical trials · 2017Trial
- Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.The New England journal of medicine · 2017Trial
- Trial
- Trial
- Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma.The European respiratory journal · 2014Trial
- Validation and psychometric properties of the Asthma Control Questionnaire among children.The Journal of allergy and clinical immunology · 2014Trial
- DASH for asthma: a pilot study of the DASH diet in not-well-controlled adult asthma.Contemporary clinical trials · 2013Trial
- Implementation Lessons From a Randomized Trial Integrating Community Asthma Education for Children.The Journal of ambulatory care managementTrial
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundCurrent asthma guidelines recommend assessing the level of a patient's asthma control. Consequently, there is increasing use of asthma control as an outcome measure in clinical research studies. Several composite assessment instruments have been developed to measure asthma control.
objectiveNational Institutes of Health institutes and federal agencies convened an expert group to propose the most appropriate standardized composite score of asthma control instruments to be used in future asthma studies.
methodsWe conducted a comprehensive search of PubMed using both the National Library of Medicine's Medical Subject Headings and key terms to identify studies that attempted to develop and/or test composite score instruments for asthma control. We classified instruments as core (required in future studies), supplemental (used according to study aims and standardized), or emerging (requiring validation and standardization). This work was discussed at a National Institutes of Health-organized workshop convened in March 2010 and finalized in September 2011.
resultsWe identified 17 composite score instruments with published validation information; all had comparable content. Eight instruments demonstrated responsiveness over time; 3 demonstrated responsiveness to treatment. A minimal clinically important difference has been established for 3 instruments. The instruments have demographic limitations; some are proprietary, and their use could be limited by cost.
conclusionTwo asthma composite score instruments are sufficiently validated for use in adult populations, but additional research is necessary to validate their use in nonwhite populations. Gaps also exist in validating instruments for pediatric populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.