Evidence map›Paper›PMID 22386506›Full record

ReviewThe Journal of allergy and clinical immunology2012

Mediators of asthma outcomes.

Cynthia S Rand, Rosalind J Wright, Michael D Cabana, Michael B Foggs, Jill S Halterman, Lynn Olson, William M Vollmer, Sandra R Wilson, Virginia Taggart

Abstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Influence of social support on asthma self-management in adolescents.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021
    Trial
  2. Trial
  3. Trial
  4. Fostering Effective Asthma Self-Management Transfer in High-Risk Children: Gaps and Opportunities for Family Engagement.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners
    Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. An integrated operational definition and conceptual model of asthma self-management in teens.The Journal of asthma : official journal of the Association for the Care of Asthma · 2018
    Article
  11. Article
  12. Review
  13. Article
  14. Perceptions and experiences underlying self-management and reporting of symptoms in teens with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2017
    Article
  15. Article
  16. Asthma phenotypes in inner-city children.The Journal of allergy and clinical immunology · 2016
    Article
  17. Article
  18. Article
  19. Experiences addressing health-related financial challenges with disease management among African American women with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2014
    Article
  20. Asthma across the ages: knowledge gaps in childhood asthma.The Journal of allergy and clinical immunology · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cynthia S RandJohns Hopkins University, Baltimore, MD, USA.
Rosalind J Wright
Michael D Cabana
Michael B Foggs
Jill S Halterman
Lynn Olson
William M Vollmer
Sandra R Wilson
Virginia Taggart

Funding

Perinatal Programming of Infant Stress Reactivity and the Atopic PhenotypeR01HL095606 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOSQUET ENLOW, MICHELLE A, WRIGHT, ROSALIND J · 2010 to 2013
$3.1M
Intramural NIH HHS Z99 AI999999NHLBI NIH HHS R01 HL095606
6 · The paper itself

Abstract

backgroundPatient adherence, the level of asthma self-management skills, exposure to stress, and depression can have considerable influence on a wide range of asthma outcomes and thus are considered asthma outcome mediators.

objectiveNational Institutes of Health institutes and other federal agencies convened an expert group to recommend standardized measures for 7 domains of asthma clinical research outcomes measures. Although the review of mediators of these outcomes was not within the scope of any specific outcome topic, a brief summary is presented so that researchers might consider potential mediators.

methodsWe prepared a summary of key mediators of asthma outcomes based on expertise and knowledge of the literature.

resultsThe rationale for including measures of adherence, self-management skills, and exposures to stress in asthma clinical research is presented, along with a brief review of instruments for collecting this information from clinical research participants.

conclusionsAppropriate measurement of adherence, self-management skills, and exposures to stress will enhance characterization of study participants and provide information about the potential impact these factors can have on mediating the effects of treatment interventions.

Indexed as

AsthmaBiomedical ResearchDepressionHumansPatient CompliancePatient Education as TopicSelf CareStress, PsychologicalTreatment Outcome

Identifiers

PMID22386506
PMCPMC4261222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.