ArticleThe Kaohsiung journal of medical sciences2012
Evaluation of the biocompatibility of a coating material for an implantable bladder volume sensor.
Article in The Kaohsiung journal of medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 78 citations in OpenAlex.
- Preclinical development of engineered biomaterial-based artificial bladder demonstrating core functions in a large-animal orthotopic model.Materials today. Bio · 2026Article
- The Magnet-Actuated Craniofacial (MAC) Distraction System: Magnetic Coupling Modeling.Annals of biomedical engineering · 2026Article
- BPEI-Stabilized Photocatalytic Au/Titania Nanoclusters with Enhanced Antimicrobial Activity for Wound Healing Applications.International journal of nanomedicine · 2025Article
- Intelligent Ureteral Stent Placeable via Standard Procedure for Kidney Pressure Telemetry: An Ex-Vivo Study.Annals of biomedical engineering · 2025Article
- Transformation gap from research findings to large-scale commercialized products in microfluidic field.Materials today. Bio · 2024Review
- Recent Advances of PDMS In Vitro Biomodels for Flow Visualizations and Measurements: From Macro to Nanoscale Applications.Micromachines · 2024Review
- Preparation and properties of silver-carrying nano-titanium dioxide antimicrobial agents and silicone composite.Scientific reports · 2024Article
- Simultaneous Effect of EBR on LLDPE and PDMS Rubber Blends and Its Nanocomposites for Cable Applications.ACS omega · 2024Article
- Flexible high-density microelectrode arrays for closed-loop brain-machine interfaces: a review.Frontiers in neuroscience · 2024Review
- In situ sensing physiological properties of biological tissues using wireless miniature soft robots.Science advances · 2023Article
- Enhanced Tumor Accumulation of Multimodal Magneto-Plasmonic Nanoparticles via an Implanted Micromagnet-Assisted Delivery Strategy.Advanced healthcare materials · 2023Article
- Mechanical Characterization and Analysis of Different-Type Polyimide Feedthroughs Based on Tensile Test and FEM Simulation for an Implantable Package.Micromachines · 2022Article
- Implantable biosensors for musculoskeletal health.Connective tissue research · 2022Review
- Hydrophobic Recovery of PDMS Surfaces in Contact with Hydrophilic Entities: Relevance to Biomedical Devices.Materials (Basel, Switzerland) · 2022Article
- KrF Laser and Plasma Exposure of PDMS-Carbon Composite and Its Antibacterial Properties.Materials (Basel, Switzerland) · 2022Article
- Properties and Applications of PDMS for Biomedical Engineering: A Review.Journal of functional biomaterials · 2021Review
- Polymer-Based Biocompatible Packaging for Implantable Devices: Packaging Method, Materials, and Reliability Simulation.Micromachines · 2021Review
- Soft, Conductive, Brain-Like, Coatings at Tips of Microelectrodes Improve Electrical Stability under Chronic, In Vivo Conditions.Micromachines · 2021Article
- Flexible Hybrid Electrodes for Continuous Measurement of the Local Temperature in Long-Term Wounds.Sensors (Basel, Switzerland) · 2021Article
- Designing and Implementing an Implantable Wireless Micromanometer System for Real-Time Bladder Pressure Monitoring: A Preliminary Study.Sensors (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the applications for implantable medical devices have increased, the need for biocompatible packaging materials has become important. Recently, we reported an implantable sensor for real-time monitoring of the changes in bladder volume, which necessitated finding a safe coating material for use in bladder tissue. At present, materials like polyethylene glycol (PEG), polydimethylsiloxane (PDMS) and parylene-C are used in biomedical devices or as coating materials, owing to their excellent safety in various medical fields. However, few studies have assessed their safety in bladder tissue, therefore, we evaluated the biocompatibility of PEG, PDMS and parylene-C in the bladder. All three materials turned out to be safe in in vitro tests of live/dead staining and cell viability. In vivo tests with hematoxylin and eosin and immunofluorescence staining with MAC387 showed no persistent inflammation. Therefore, we consider that the three materials are biocompatible in bladder tissue. Despite this safety, however, PEG has biodegradable characteristics and thus is not suitable for use as packaging. We suggest that PDMS and parylene-C can be used as safe coating materials for the implantable bladder volume sensor reported previously.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.