ArticleOrganic letters2012
Nickel-catalyzed cross-coupling of chromene acetals and boronic acids.
Article in Organic letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Development, Application, and Mechanistic Interrogation of a Dual Ni Catalysis Approach to Photoredox-Based C(spJournal of the American Chemical Society · 2025Article
- C-H Bond Functionalization of N-Heteroarenes Mediated by Selectfluor.Topics in current chemistry (Cham) · 2023Review
- Expedient access to saturated nitrogen heterocycles by photoredox cyclization of imino-tethered dihydropyridines.Chemical science · 2019Article
- Nickel-Catalyzed Stille Cross Coupling of C-O Electrophiles.ACS catalysis · 2019Article
- Article
- Copper-catalyzed oxidative cross-dehydrogenative coupling of 2H-chromenes and terminal alkynes.Organic & biomolecular chemistry · 2018Article
- Ni-Catalyzed Carbon-Carbon Bond-Forming Reductive Amination.Journal of the American Chemical Society · 2018Article
- Mechanism and Origins of Ligand-Controlled Stereoselectivity of Ni-Catalyzed Suzuki-Miyaura Coupling with Benzylic Esters: A Computational Study.Journal of the American Chemical Society · 2017Article
- Parameterization of phosphine ligands demonstrates enhancement of nickel catalysis via remote steric effects.Nature chemistry · 2017Article
- A modular, air-stable nickel precatalyst.Organic letters · 2015Article
- Brønsted Acid/Lewis Acid Cooperatively Catalyzed Addition of Diazoester to 2European journal of organic chemistry · 2014Article
- Catalytic enantioselective synthesis of 2-aryl-chromenes.Chemical science · 2014Article
- Metalloradical approach to 2H-chromenes.Journal of the American Chemical Society · 2014Article
- Bimolecular Coupling Reactions through Oxidatively Generated Aromatic Cations: Scope and Stereocontrol.Tetrahedron · 2013Article
- Nickel-catalyzed enantioselective arylation of pyridinium ions: harnessing an iminium ion activation mode.Angewandte Chemie (International ed. in English) · 2013Article
- Mechanistic investigation of the nickel-catalyzed Suzuki reaction of N,O-acetals: evidence for boronic acid assisted oxidative addition and an iminium activation pathway.Journal of the American Chemical Society · 2012Article
- Aromatic cations from oxidative carbon-hydrogen bond cleavage in bimolecular carbon-carbon bond forming reactions.The Journal of organic chemistry · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
A modular and highly efficient protocol for the synthesis of 2-aryl- and heteroaryl-2H-chromenes is described. Under base-free conditions, readily accessible 2-ethoxy-2H-chromenes undergo C(sp(3))-O activation and C(sp(3))-C bond formation in the presence of an inexpensive nickel catalyst and boronic acids. This new strategy enables broad access to 2-substituted-2H-chromenes and has been applied to the late-stage incorporation of complex molecules, including the pharmaceuticals loratidine and indomethacin methyl ester.
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Registered trials
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