Evidence map›Paper›PMID 22385191›Full record

ArticleNanomedicine (London, England)2012

Are high drug loading nanoparticles the next step forward for chemotherapy?

Joseph Della Rocca, Demin Liu, Wenbin Lin

Abstract readEditorial
In one paragraph

Article in Nanomedicine (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  18. Article
  19. Liposomal spherical nucleic acids.Journal of the American Chemical Society · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joseph Della Rocca
Demin Liu
Wenbin Lin

Funding

"Smart" Nanoparticles for Cancer Therapy and ImagingU54CA119343 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VAN DYKE, TERRY A · 2005 to 2009
$18.3M
Translational Nanosystems for Improved Lung Cancer Treatment with Small MoleculesU54CA151652 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DESIMONE, JOSEPH M. · 2010 to 2014
$12.1M
Nanoscale Metal-organic Frameworks for Imaging and Therapy of Pancreatic CancerU01CA151455 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIN, WENBIN, YEH, JEN JEN · 2010 to 2014
$2.1M
NCI NIH HHS U01 CA151455NCI NIH HHS U01-CA151455NCI NIH HHS U54 CA119343NCI NIH HHS U54 CA151652NCI NIH HHS U54-CA151652
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsDrug CarriersHumansNanoparticlesNeoplasmsAntineoplastic AgentsDrug Carriers

Identifiers

PMID22385191
PMCPMC3777216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.