Evidence map›Paper›PMID 22384820›Full record

ArticleACS combinatorial science2012

Facile (triazolyl)methylation of MACOS-derived benzofused sultams utilizing ROMP-derived OTP reagents.

Saqib Faisal, Farman Ullah, Pradip K Maity, Alan Rolfe, Thiwanka B Samarakoon, Patrick Porubsky, Benjamin Neuenswander, Gerald H Lushington, Fatima Z Basha, Michael G Organ and 1 more

Abstract read
In one paragraph

Article in ACS combinatorial science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saqib FaisalDepartment of Chemistry, University of Kansas, Lawrence, 66045-7582, United States.
Farman Ullah
Pradip K Maity
Alan Rolfe
Thiwanka B Samarakoon
Patrick Porubsky
Benjamin Neuenswander
Gerald H Lushington
Fatima Z Basha
Michael G Organ
Paul R Hanson

Funding

Phase trafficking in combinatorial chemistry: ROM polymerizationP50GM069663 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY · 2003 to 2012
$18.9M
Probing Diversity Space with Novel Pilot Scale LibrariesP41GM076302 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HANSON, PAUL R. · 2005 to 2010
$2.6M
ROMP-Derived Oligomers for Facilitated SynthesisR42GM076765 · NIGMS · MATERIA, INC. · PI HANSON, PAUL R. · 2009 to 2010
$826k
ROMP-Derived Oligomers for Faciliated SynthesisR41GM076765 · NIGMS · MATERIA, INC. · PI HANSON, PAUL R. · 2006 to 2006
$174k
NIGMS NIH HHS P41 GM076302NIGMS NIH HHS P41-GM076302NIGMS NIH HHS P50 GM069663NIGMS NIH HHS R41 GM076765NIGMS NIH HHS R42 GM076765
6 · The paper itself

Abstract

A combination of MACOS scale-out and ROMP-derived oligomeric triazole phosphates (OTP(n)) have been successfully utilized for the preparation of a 106-member library of triazole containing benzothiaoxazepine-1,1-dioxides. This report demonstrates the utilization of a suite of soluble OTP(n) reagents for facile (triazolyl)methylation of 10 MACOS-derived sultam scaffolds in purification-free process for parallel synthesis of small molecule collections for HTS.

Indexed as

MicrowavesBenzothiadiazinesCombinatorial Chemistry TechniquesMethylationMolecular StructureOxidesPhosphatesSmall Molecule LibrariesStereoisomerismTriazolesBenzothiadiazinesOxidesPhosphatesSmall Molecule LibrariesTriazoles

Identifiers

PMID22384820
PMCPMC3656824

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.