ArticleBiochemia medica2012
Relationship between serum interleukin-1beta levels and acute phase response proteins in patients with familial Mediterranean fever.
Article in Biochemia medica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What is the best acute phase reactant for familial Mediterranean fever follow-up and its role in the prediction of complications? A systematic review.Rheumatology international · 2016Pooled it
- Clinical description, genetic analysis and characterization of two NLRP12 heterozygous VUS variants.Frontiers in immunology · 2026Article
- miR-21 and cathepsin B in familial Mediterranean fever: novel findings regarding their impact on disease severity.BMJ paediatrics open · 2025Article
- Ultrasound Measurement of Femoral Cartilage Thickness in Patients with Familial Mediterranean Fever and its Relation to Amyloidosis and Other Disease Characteristics.Sisli Etfal Hastanesi tip bulteni · 2022Article
- Does Familial Mediterranean Fever Provoke Atherosclerosis in Children? Evaluation of Arterial Stiffness and Serum Endocan Levels.Clinical rheumatology · 2021Article
- Is there a relationship between serum omentin level and acute phase response in patients with familial Mediterranean fever?Clinical rheumatology · 2021Article
- Evaluation of hematological parameters in children with FMF.Clinical rheumatology · 2019Article
- Subclinical inflammation in a case of menstruation-induced familial Mediterranean fever: A case report.Medicine · 2018Article
- Can the Thiol/Disulfide Imbalance Be a Predictor of Colchicine Resistance in Familial Mediterranean Fever?Journal of Korean medical science · 2017Article
- Aortic Flow Propagation Velocity in Patients with Familial Mediterranean Fever: an Observational Study.Korean circulation journal · 2017Article
- Assessment of neutrophil to lymphocyte ratio and mean platelet volume in pediatric familial Mediterranean fever patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Evaluation of IL-1β, IL-1ra, and IL-10 levels and outcome of periodontal therapy in chronic periodontitis with familial Mediterranean fever.Clinical oral investigations · 2017Article
- The Relationship Among the Level of Serum Amyloid A, High-Density Lipoprotein and Microalbuminuria in Patients With Familial Mediterranean Fever.Journal of clinical laboratory analysis · 2016Article
- Simple markers for subclinical inflammation in patients with Familial Mediterranean Fever.Medical science monitor : international medical journal of experimental and clinical research · 2015Article
- Is neutrophil/lymphocyte ratio associated with subclinical inflammation and amyloidosis in patients with familial Mediterranean fever?BioMed research international · 2013Article
- Comparison of optical coherence tomography angiography results of adult patients with Familial Mediterranean fever and healthy individuals.Therapeutic advances in ophthalmologyArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to investigate whether serum levels of interleukin-1beta (IL-1beta) has any possible correlation on inflammatory parameters such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and fibrinogen concentration in patients with familial Mediterranean fever (FMF) patients during attack-free period. MATERIALS AND
methodsThe serum levels of IL-1beta, as an indicator of cytokines status, and the acute phase response proteins, CRP, ESR and fibrinogen levels were evaluated in 35 attack-free patients with FMF and 25 healthy volunteers.
resultsSerum IL-1beta levels were significantly higher in patients with FMF than control subjects (P = 0.018). There was no statistically significant difference in the serum levels of ESR, CRP and fibrinogen between two groups (P = 0.181, P = 0.816, P = 0.686, respectively). There was a significant correlation between IL-1beta and CRP (r = 0.513, P = 0.002) values of FMF group.
conclusionsIn conclusion, our results confirm the presence of increased IL-1beta levels in FMF patients during attack-free period. Serum IL-1beta values seems to correlate with CRP levels. The elevation of IL-1beta levels may be important in monitoring subclinical inflammation of attack free period in FMF patients.
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