ArticleG3 (Bethesda, Md.)2012
Haplotype probabilities in advanced intercross populations.
Article in G3 (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Leveraging low-cost short-read sequencing: revolutionizing complex trait genetics.Molecular biology and evolution · 2026Article
- Low-coverage whole-genome sequencing facilitates accurate and cost-effective haplotype reconstruction in complex mouse crosses.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Article
- Article
- Celebrating discovery across the tree of life.G3 (Bethesda, Md.) · 2023Article
- A generic hidden Markov model for multiparent populations.G3 (Bethesda, Md.) · 2022Article
- Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice.Genetics · 2021Article
- Mouse Genetic Reference Populations: Cellular Platforms for Integrative Systems Genetics.Trends in genetics : TIG · 2021Review
- Genetic Architecture Modulates Diet-Induced Hepatic mRNA and miRNA Expression Profiles in Diversity Outbred Mice.Genetics · 2020Article
- Cleaning Genotype Data from Diversity Outbred Mice.G3 (Bethesda, Md.) · 2019Article
- R/qtl2: Software for Mapping Quantitative Trait Loci with High-Dimensional Data and Multiparent Populations.Genetics · 2019Article
- Article
- Article
- Mapping QTL Contributing to Variation in Posterior Lobe Morphology between Strains of Drosophila melanogaster.PloS one · 2016Article
- Modeling X-linked ancestral origins in multiparental populations.G3 (Bethesda, Md.) · 2015Article
- Quantitative trait locus mapping methods for diversity outbred mice.G3 (Bethesda, Md.) · 2014Article
- High-resolution genetic mapping of complex traits from a combined analysis of F2 and advanced intercross mice.Genetics · 2014Article
- A general modeling framework for genome ancestral origins in multiparental populations.Genetics · 2014Article
- RNA-Seq alignment to individualized genomes improves transcript abundance estimates in multiparent populations.Genetics · 2014Article
- Discovery and refinement of muscle weight QTLs in B6 × D2 advanced intercross mice.Physiological genomics · 2014Article
- Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Advanced intercross populations, in which multiple inbred strains are mated at random for many generations, have the advantage of greater precision of genetic mapping because of the accumulation of recombination events across the multiple generations. Related designs include heterogeneous stock and the diversity outcross population. In this article, I derive the two-locus haplotype probabilities on the autosome and X chromosome with these designs. These haplotype probabilities provide the key quantities for developing hidden Markov models for the treatment of missing genotype information. I further derive the map expansion in these populations, which is the frequency of recombination breakpoints on a random chromosome.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.