ArticleG3 (Bethesda, Md.)2012
Linkage and Physical Mapping of Sex Region on LG23 of Nile Tilapia (Oreochromis niloticus).
Article in G3 (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
48 citing papers in PubMed, 91 citations in OpenAlex.
- Before the East African Radiation: Sex Chromosome Systems in Basal Haplotilapiine Cichlids.Genome biology and evolution · 2026Article
- A Y-linked duplication of anti-Mullerian hormone is the sex determination gene in threespine stickleback.PLoS genetics · 2025Article
- Master-Key Regulators of Sex Determination in Fish and Other Vertebrates-A Review.International journal of molecular sciences · 2023Review
- Animal board invited review: Widespread adoption of genetic technologies is key to sustainable expansion of global aquaculture.Animal : an international journal of animal bioscience · 2022Review
- Molecular Cloning and Expression Responses ofGenes · 2022Article
- First identification of two co-existing genome-wide significant sex quantitative trait loci (QTL) in red tilapia using integrative QTL mapping.Zoological research · 2022Article
- Roles of anti-Müllerian hormone and its duplicates in sex determination and germ cell proliferation of Nile tilapia.Genetics · 2022Article
- Gene Variant ofInternational journal of molecular sciences · 2021Article
- Origin of a Giant Sex Chromosome.Molecular biology and evolution · 2021Article
- A Chromosome-Level Genome Assembly of the Mandarin Fish (Frontiers in genetics · 2021Article
- Article
- Structure and Sequence of the Sex Determining Locus in Two Wild Populations of Nile Tilapia.Genes · 2020Article
- Sex determination in the GIFT strain of tilapia is controlled by a locus in linkage group 23.BMC genetics · 2020Article
- Preferential Mapping of Sex-Biased Differentially-Expressed Genes of Larvae to the Sex-Determining Region of Flathead Grey Mullet (Frontiers in genetics · 2020Article
- Mapping of the Sex Determining Region on Linkage Group 12 of Guppy (G3 (Bethesda, Md.) · 2019Article
- Fine Mapping Using Whole-Genome Sequencing Confirms Anti-Müllerian Hormone as a Major Gene for Sex Determination in Farmed Nile Tilapia (G3 (Bethesda, Md.) · 2019Article
- Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes.GigaScience · 2019Article
- Marker-assisted selection of YY supermales from a genetically improved farmed tilapia-derived strain.Zoological research · 2019Article
- Article
- Mismatches between the genetic and phenotypic sex in the wild Kou population of Nile tilapiaPeerJ · 2019Article
Corrections and comments
- Erratum issuedCorrigendum.2016
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence supports that sex determination (SD) in tilapia is controlled by major genetic factors that may interact with minor genetic as well as environmental factors, thus implying that SD should be analyzed as a quantitative trait. Quantitative trait loci (QTL) for SD in Oreochromis niloticus were previously detected on linkage groups (LG) 1 and 23. Twenty-one short single repeats (SSR) of >12 TGs and one single nucleotide polymorphism were identified using the unpublished tilapia genome sequence on LG23. All markers showed two segregating alleles in a mapping family that was obtained by a cross between O. niloticus male (XY) and sex-reversed female (ΔXY) yielding 29 females (XX) and 61 males (XY and YY). Interval mapping analysis mapped the QTL peak between SSR markers ARO172 and ARO177 with a maximum F value of 78.7 (P < 7.6 × 10(-14)). Twelve adjacent markers found in this region were homozygous in females and either homozygous for the alternative allele or heterozygous in males. This segment was defined as the sex region (SR). The SR encompasses 1.5 Mbp on a single tilapia scaffold (no. 101) harboring 51 annotated genes. Among 10 candidate genes for SD that were tested for gene expression, anti-Müllerian hormone (Amh), which is located in the center of the SR, showed the highest overexpression in male vs. female embryos at 3 to 7 days postfertilization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.