Evidence map›Paper›PMID 22384360›Full record

ArticleG3 (Bethesda, Md.)2011

Genetic Background and Allorecognition Phenotype in Hydractinia symbiolongicarpus.

Anahid E Powell, Maria Moreno, Andrea Gloria-Soria, Fadi G Lakkis, Stephen L Dellaporta, Leo W Buss

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Making Neurobots and Chimerical Ctenophores.bioRxiv : the preprint server for biology · 2024
    Article
  2. A family of unusual immunoglobulin superfamily genes in an invertebrate histocompatibility complex.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anahid E Powell
Maria Moreno
Andrea Gloria-Soria
Fadi G Lakkis
Stephen L Dellaporta
Leo W Buss

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007499 · NIGMS · YALE UNIVERSITY · PI CARLSON, JOHN R, REINKE, VALERIE J · 1985 to 2022
$13.9M
A Model Organism to Study Allorecognition and ChimerismR56AI079103 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUSS, LEO WILLIAM, DELLAPORTA, STEPHEN L · 2009 to 2009
$417k
NIAID NIH HHS R56 AI079103NIGMS NIH HHS T32 GM007499
6 · The paper itself

Abstract

The Hydractinia allorecognition complex (ARC) was initially identified as a single chromosomal interval using inbred and congenic lines. The production of defined lines necessarily homogenizes genetic background and thus may be expected to obscure the effects of unlinked allorecognition loci should they exist. Here, we report the results of crosses in which inbred lines were out-crossed to wild-type animals in an attempt to identify dominant, codominant, or incompletely dominant modifiers of allorecognition. A claim for the existence of modifiers unlinked to ARC was rejected for three different genetic backgrounds. Estimates of the genetic map distance of ARC in two wild-type haplotypes differed markedly from one another and from that measured in congenic lines. These results suggest that additional allodeterminants exist in the Hydractinia ARC.

Indexed as

cnidarianhydroidinvertebrate immunityrecognition

Identifiers

PMID22384360
PMCPMC3276163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.