Evidence map›Paper›PMID 22384326›Full record

ArticleG3 (Bethesda, Md.)2011

A Screen for Germination Mutants in Saccharomyces cerevisiae.

Anne Kloimwieder, Fred Winston

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. mNature communications · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Leveraging a high resolution microfluidic assay reveals insights into pathogenic fungal spore germination.Integrative biology : quantitative biosciences from nano to macro · 2016
    Article
  18. Article
  19. Article
  20. Applied usage of yeast spores as chitosan beads.Applied and environmental microbiology · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anne KloimwiederDepartment of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
Fred Winston

Funding

GENERAL TRANSCRIPTION FACTORS IN YEASTR01GM045720 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WINSTON, FRED M. · 1991 to 2011
$5.3M
NIGMS NIH HHS R01 GM045720
6 · The paper itself

Abstract

Spore germination in Saccharomyces cerevisiae is a process in which a quiescent cell begins to divide. During germination, the cell undergoes dramatic changes in cell wall and membrane composition, as well as in gene expression. To understand germination in greater detail, we screened the S. cerevisiae deletion set for germination mutants. Our results identified two genes, TRF4 and ERG6, that are required for normal germination on solid media. TRF4 is a member of the TRAMP complex that, together with the exosome, degrades RNA polymerase II transcripts. ERG6 encodes a key step in ergosterol biosynthesis. Taken together, these results demonstrate the complex nature of germination and two genes important in the process.

Indexed as

ERG6germinationSaccharomyces cerevisiaesporulationTRF4

Identifiers

PMID22384326
PMCPMC3276131

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.