ArticlePloS one2012
Mosaic origins of a complex chimeric mitochondrial gene in Silene vulgaris.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Differentially Expressed Genes Shared by Two Distinct Cytoplasmic Male Sterility (CMS) Types ofCells · 2020Article
- Article
- Homologous recombination changes the context of Cytochrome b transcription in the mitochondrial genome of Silene vulgaris KRA.BMC genomics · 2018Article
- The Role of Non-Coding RNAs in Cytoplasmic Male Sterility in Flowering Plants.International journal of molecular sciences · 2017Review
- Non-coding RNA may be associated with cytoplasmic male sterility in Silene vulgaris.Journal of experimental botany · 2017Article
- The application of RNA-seq to the comprehensive analysis of plant mitochondrial transcriptomes.Molecular genetics and genomics : MGG · 2015Review
- Transcription of atp1 is influenced by both genomic configuration and nuclear background in the highly rearranged mitochondrial genomes of Silene vulgaris.Plant molecular biology · 2013Article
- Next-generation sequencing of mitochondrial targeted AAV transfer of human ND4 in mice.Molecular vision · 2013Article
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chimeric genes are significant sources of evolutionary innovation that are normally created when portions of two or more protein coding regions fuse to form a new open reading frame. In plant mitochondria astonishingly high numbers of different novel chimeric genes have been reported, where they are generated through processes of rearrangement and recombination. Nonetheless, because most studies do not find or report nucleotide variation within the same chimeric gene, evolution after the origination of these chimeric genes remains unstudied. Here we identify two alleles of a complex chimera in Silene vulgaris that are divergent in nucleotide sequence, genomic position relative to other mitochondrial genes, and expression patterns. Structural patterns suggest a history partially influenced by gene conversion between the chimeric gene and functional copies of subunit 1 of the mitochondrial ATP synthase gene (atp1). We identified small repeat structures within the chimeras that are likely recombination sites allowing generation of the chimera. These results establish the potential for chimeric gene divergence in different plant mitochondrial lineages within the same species. This result contrasts with the absence of diversity within mitochondrial chimeras found in crop species.
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