ReviewJournal of the American Society of Nephrology : JASN2012
Cardiovascular disease in children with chronic kidney disease.
Review in Journal of the American Society of Nephrology : JASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 183 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation Of Cardiac Function In Children 0n Regular Heamodialysis
Arterial Stiffness in Children and Young People With Hypertension and Chronic Kidney Disease
Who cites it
183 citing papers in PubMed, 3 syntheses or guidelines pooled it, 405 citations in OpenAlex.
- Ambulatory hypertension and left ventricular hypertrophy in pediatric chronic kidney disease: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- Management of blood pressure in adults, children and young people on dialysis: UK kidney association clinical practice guideline.BMC nephrology · 2025Guideline
- A systematic review of symptoms experienced by children and young people with kidney failure.Pediatric nephrology (Berlin, Germany) · 2025Pooled it
- Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial.The Lancet. Child & adolescent health · 2023Trial
- Short, frequent, 5-days-per-week, in-center hemodialysis versus 3-days-per week treatment: a randomized crossover pilot trial through the Midwest Pediatric Nephrology Consortium.Pediatric nephrology (Berlin, Germany) · 2017Trial
- Feasibility and acceptability of a telehealth-supported physical activity program for children with chronic kidney disease: a pilot mixed methods study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Hypertension control and its association with left ventricular hypertrophy in children and young people on dialysis: a longitudinal study.Pediatric nephrology (Berlin, Germany) · 2026Article
- The epidemiology of kidney and urinary tract infections in pediatric chronic kidney disease: prevalence, risk factors and association with GFR decline in the Chronic Kidney Disease in Children Study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Left ventricular remodeling by cardiac magnetic resonance in children with advanced chronic kidney disease: an analysis of the Chronic Kidney Disease in Children (CKiD) study.Pediatric nephrology (Berlin, Germany) · 2026Article
- Profile of FGF23 and NTproBNP levels and their association with left ventricular hypertrophy in children and adolescents with CKD.International urology and nephrology · 2026Article
- Arterial stiffening in children with early chronic kidney disease is associated with blood pressure but not decline in kidney function: a longitudinal study from the HOT-KID cohort.Pediatric nephrology (Berlin, Germany) · 2026Article
- Interdialytic weight gain, carotid intima media thickness, and cardiovascular profile in children undergoing chronic hemodialysis: a multicenter study.BMC nephrology · 2026Article
- Markers of Mineral Metabolism in Children With CKD Stages 2 to 5D.Kidney international reports · 2026Article
- Age-Stratified Performance of the TAPSE/sPAP Ratio as a Marker of Right Ventricular-Pulmonary Arterial Coupling in Chronic Kidney Disease.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Association of Perinatal HIV Exposure and HIV Disease Severity With BP in Youth.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Saudi Heart Association Scientific Statement on Cardiovascular-Kidney-Liver-Metabolic (CKLM) Syndrome.Journal of the Saudi Heart Association · 2026Article
- Machine Learning Reveals Novel Pediatric Heart Failure Phenotypes with Distinct Mortality and Hospitalization Outcomes.Diagnostics (Basel, Switzerland) · 2025Article
- Long-term kidney complications in childhood leukemia survivors: a study from the Childhood and Adolescent Leukemia (LEA) project.Haematologica · 2025Article
- Article
- Interval healthcare provider contact and blood pressure control in children with chronic kidney disease and hypertension.Pediatric nephrology (Berlin, Germany) · 2025Article
123 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
More than a decade ago, cardiovascular disease (CVD) was recognized as a major cause of death in children with advanced CKD. This observation has sparked the publication of multiple studies assessing cardiovascular risk, mechanisms of disease, and early markers of CVD in this population. Similar to adults, children with CKD have an extremely high prevalence of traditional and uremia-related CVD risk factors. Early markers of cardiomyopathy, such as left ventricular hypertrophy and dysfunction, and early markers of atherosclerosis, such as increased carotid artery intima-media thickness, carotid arterial wall stiffness, and coronary artery calcification, are frequently present in these children, especially those on maintenance dialysis. As a population without preexisting symptomatic cardiac disease, children with CKD potentially receive significant benefit from aggressive attempts to prevent and treat CVD. Early CKD, before needing dialysis, is the optimal time to both identify modifiable risk factors and intervene in an effort to avert future CVD. Slowing the progression of CKD, avoiding long-term dialysis and, if possible, conducting preemptive transplantation may represent the best strategies to decrease the risk of premature cardiac disease and death in children with CKD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.