ArticleCBE life sciences education2012
Visualizing protein interactions and dynamics: evolving a visual language for molecular animation.
Article in CBE life sciences education, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Understanding chemical reactions through multimedia resolution data artistic educational tool (MRDAET).Protein science : a publication of the Protein Society · 2026Article
- Designing Biochemical Visual Literacy Assessments: Insights from Classroom Testing and Student Interviews.Journal of chemical education · 2025Article
- Design principles for molecular animation.Frontiers in bioinformatics · 2024Article
- Seeing the unseen: Comparison study of representation approaches for biochemical processes in education.PloS one · 2023Review
- Considering best practices in color palettes for molecular visualizations.Journal of integrative bioinformatics · 2022Article
- Article
- Immersive 3D Experience of Osmosis Improves Learning Outcomes of First-Year Cell Biology Students.CBE life sciences education · 2021Article
- Article
- Molecular Concepts Adaptive Assessment (MCAA) Characterizes Undergraduate Misconceptions about Molecular Emergence.CBE life sciences education · 2019Article
- Efficacy of a Meiosis Learning Module Developed for the Virtual Cell Animation Collection.CBE life sciences education · 2017Article
- Physical models have gender-specific effects on student understanding of protein structure-function relationships.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology · 2016Article
- Immune attack players perform better on a test of cellular immunology and self confidence than their classmates who play a control video game.Faraday discussions · 2014Article
- Misconceptions are "so yesterday!".CBE life sciences education · 2013Article
- 3D-Printed Protein Models as an Educational Tool in Biochemistry Outreach.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular BiologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Undergraduate biology education provides students with a number of learning challenges. Subject areas that are particularly difficult to understand include protein conformational change and stability, diffusion and random molecular motion, and molecular crowding. In this study, we examined the relative effectiveness of three-dimensional visualization techniques for learning about protein conformation and molecular motion in association with a ligand-receptor binding event. Increasingly complex versions of the same binding event were depicted in each of four animated treatments. Students (n = 131) were recruited from the undergraduate biology program at University of Toronto, Mississauga. Visualization media were developed in the Center for Molecular and Cellular Dynamics at Harvard Medical School. Stem cell factor ligand and cKit receptor tyrosine kinase were used as a classical example of a ligand-induced receptor dimerization and activation event. Each group completed a pretest, viewed one of four variants of the animation, and completed a posttest and, at 2 wk following the assessment, a delayed posttest. Overall, the most complex animation was the most effective at fostering students' understanding of the events depicted. These results suggest that, in select learning contexts, increasingly complex representations may be more desirable for conveying the dynamic nature of cell binding events.
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Registered trials
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