Evidence map›Paper›PMID 22383082›Full record

ArticleDigestive diseases and sciences2012

Clinical characteristics of young-onset ischemic colitis.

Takefumi Kimura, Akihiro Shinji, Akira Horiuchi, Naoki Tanaka, Tadanobu Nagaya, Takashi Shigeno, Naoshi Nakamura, Michiharu Komatsu, Takeji Umemura, Norikazu Arakura and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Guideline
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  4. AI-Based Platelet-Independent Noninvasive Test for Liver Fibrosis in MASLD Patients.JGH open : an open access journal of gastroenterology and hepatology · 2025
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  6. Review
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  11. Ischemic colitis as a cause of severe hematochezia: A mini review.Journal of clinical and experimental gastroenterology · 2022
    Article
  12. Article
  13. Rare Clinical Association betweenMedicina (Kaunas, Lithuania) · 2021
    Review
  14. Population-Based Study of the Clinical Characteristics and Risk Factors of Ischemic Colitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  15. Diagnostic methods and drug therapies in patients with ischemic colitis.International journal of colorectal disease · 2021
    Review
  16. Low-dose aspirin and the severity of ıschemic colitis: A single-center retrospective study.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
    Article
  17. Article
  18. Ischemic Colitis Associated with Rhabdomyolysis and Heat Stroke after an Intense Exercise in Young Adult.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Takefumi KimuraDepartment of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.
Akihiro Shinji
Akira Horiuchi
Naoki Tanaka
Tadanobu Nagaya
Takashi Shigeno
Naoshi Nakamura
Michiharu Komatsu
Takeji Umemura
Norikazu Arakura
Akihiro Matsumoto
Eiji Tanaka
Ōtani University · JPShinshu University · JPKameda Medical Center · JPShinshu University Hospital · JPShowa Inan General Hospital · JPSuwa Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIschemic colitis (IC) typically develops in the elderly, where hypertension, cerebrocardiovascular disease, and past history of abdominal surgery are regarded as risk factors. Although there have been reports of younger patients with IC, its clinical features remain unclear.

aimThe aim of this study was to clarify the clinical characteristics of IC in young adults.

methodsThree hundred fifty-nine patients were diagnosed as having IC at five hospitals across Nagano prefecture, Japan. Clinical data were compared between the young patient group [20-45 years, n = 53 (15%)] and the elderly patient group [>45 years, n = 306 (85%)], as well as with age- and gender-matched healthy individuals (n = 156).

resultsThe presence of a smoking habit and hyperuricemia were significantly higher in the young patient group compared with the elderly patient group (42 vs. 19%, P = 0.001 and 8 vs. 1%, P = 0.019, respectively), which was confirmed by multiple logistic regression analysis (P = 0.001, odds ratio 3.239 and P = 0.028, odds ratio 16.907, respectively). Additionally, multiple logistic regression analysis of the young IC patient group and age- and gender-matched healthy individuals demonstrated that these two factors were strongly associated with IC development (P = 0.008, odds ratio 2.49 for smoking habit and P = 0.039, odds ratio 6.37 for hyperuricemia).

conclusionsHigh prevalences of a smoking habit and hyperuricemia are characteristic features of IC in the young adult population.

Indexed as

Life StyleAdultAgedAged, 80 and overAge FactorsAge of OnsetCase-Control StudiesColitis, IschemicColonoscopyCombined Modality TherapyComorbidityConfidence IntervalsConstipationDisease ProgressionFemaleFollow-Up Studies

Identifiers

PMID22383082
OpenAlexW2036406892

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.