Evidence map›Paper›PMID 22383000›Full record

ArticleCurrent protocols in pharmacology2012

Models of inflammation: carrageenan air pouch.

Djane B Duarte, Michael R Vasko, Jill C Fehrenbacher

Abstract read
In one paragraph

Article in Current protocols in pharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Pharmaceutics · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Anti-Inflammatory Activity ofPharmaceuticals (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Evaluation of In Vivo Wound-Healing and Anti-Inflammatory Activities of Solvent Fractions of Fruits ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Anti-Inflammatory Activity of the Essential Oil Citral in Experimental Infection withEvidence-based complementary and alternative medicine : eCAM · 2017
    Article
  18. Hyaluronidase decreases neutrophils infiltration to the inflammatory site.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Djane B DuarteDepartment of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana.
Michael R Vasko
Jill C Fehrenbacher

Funding

An intracellular signaling switch for maintaining peripheral sensitizationR01NS069915 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI VASKO, MICHAEL R · 2010 to 2013
$1.7M
EXTRAMURAL RESEARCH FACILITIES CONSTRUCTIONC06RR015481 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FIFE, ROSE S · 2001 to 2001
$1.6M
THE ROLE FOR THE GPR30 RECEPTOR IN INFLAMMATORY PAINR21DE018796 · NIDCR · INDIANA UNIVERSITY INDIANAPOLIS · PI FEHRENBACHER, JILL C · 2009 to 2010
$424k
NCRR NIH HHS C06 RR015481NIDCR NIH HHS R21 DE018796NIDCR NIH HHS R21DE18796NINDS NIH HHS R01 NS069915NINDS NIH HHS R01NS069915
6 · The paper itself

Abstract

The subcutaneous air pouch is an in vivo model that can be used to study acute and chronic inflammation, the resolution of the inflammatory response, and the oxidative stress response. Injection of irritants into an air pouch in rats or mice induces an inflammatory response that can be quantified by the volume of exudate produced, the infiltration of cells, and the release of inflammatory mediators. The model presented in this unit has been extensively used to identify potential anti-inflammatory drugs.

Indexed as

AirDisease Models, AnimalAnimalsCarrageenanExudates and TransudatesInflammationInjections, SubcutaneousLaboratory Animal ScienceMiceRatsSpecimen HandlingCarrageenan

Identifiers

PMID22383000
PMCPMC5954990

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.