Evidence map›Paper›PMID 22381678›Full record

ReviewCurrent opinion in microbiology2012

Extra cytoplasmic function σ factor activation.

Theresa D Ho, Craig D Ellermeier

Abstract readReview
In one paragraph

Review in Current opinion in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Article
  3. Insights into the Metabolic Adaptations of a Carbapenem-ResistantInternational journal of molecular sciences · 2025
    Article
  4. Roles of theFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Article
  7. σMicrobiology spectrum · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Activation of the extracytoplasmic function σ factor σCurrent opinion in microbiology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Theresa D HoDepartment of Microbiology, University of Iowa, Iowa City, IA 52242, United States.
Craig D Ellermeier

Funding

Identification of daptomycin resistance mechanisms in Clostridioides difficileR01AI087834 · NIAID · UNIVERSITY OF IOWA · PI ELLERMEIER, CRAIG D · 2011 to 2025
$5.6M
NIAID NIH HHS AI087834NIAID NIH HHS R01 AI087834
6 · The paper itself

Abstract

The bacterial cell envelope is essential for cell viability and is a target for numerous antibiotics and host immune defenses. Thus bacteria must sense and respond to damage to the cell envelope. Many bacteria utilize alternative σ factors such as extracytoplasmic function (ECF) σ factors to respond to cell envelope stress. Although ECF σ factors are utilized by both Gram negative and Gram positive bacteria to respond to cell envelope stress, the mechanisms of sensing differ. In this review, we examine the events and proteins that are required for activation of two model extracytoplasmic function σ factors, σ(E) in E. coli and σ(W) in B. subtilis.

Indexed as

Gene Expression Regulation, BacterialBacillus subtilisBacterial ProteinsEscherichia coliSigma FactorBacterial ProteinsSigma Factor

Identifiers

PMID22381678
PMCPMC3320685

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.