ArticleThe Annals of thoracic surgery2012
Heterogeneous distribution of left ventricular contractile injury in chronic aortic insufficiency.
Article in The Annals of thoracic surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- A validation of two-dimensional in vivo regional strain computed from displacement encoding with stimulated echoes (DENSE), in reference to tagged magnetic resonance imaging and studies in repeatability.Annals of biomedical engineering · 2014Trial
- Article
- Heterogeneity of systolic dysfunction in patients with severe aortic stenosis and preserved ejection fraction.Journal of cardiac surgery · 2017Article
- Reduced Longitudinal Function in Chronic Aortic Regurgitation.Journal of cardiovascular ultrasound · 2015Article
- Quantifying "normalized" regional left ventricular contractile function in ischemic coronary artery disease.The Journal of thoracic and cardiovascular surgery · 2015Article
- Early left ventricular regional contractile impairment in chronic mitral regurgitation occurs in a consistent, heterogeneous pattern.The Journal of thoracic and cardiovascular surgery · 2014Article
- Cardiac assessment in pediatric mice: strain analysis as a diagnostic measurement.Echocardiography (Mount Kisco, N.Y.) · 2014Article
- MRI-based multiparametric strain analysis predicts contractile recovery after aortic valve replacement for aortic insufficiency.Journal of cardiac surgery · 2012Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundGlobal systolic strain has been described previously in patients with chronic aortic insufficiency (AI). This study explored regional differences in contractile injury.
methodsTagged magnetic resonance images of the left ventricle (LV) were acquired and analyzed to calculate systolic strain in 42 patients with chronic AI. Multiparametric systolic strain analysis was applied to relate cardiac function in AI patients to a normal strain database (N = 60). AI patients were classified as having normal or poor function based on their results. A two-way repeated-measures analysis of variance was applied to analyze regional differences in injury.
resultsThe mean and standard deviation of raw strain values (circumferential strain, longitudinal strain, and minimum principal strain angle) are presented over the entire LV in our normal strain database. Of the 42 patients with AI, 15 could be defined as having poor function by multiparametric systolic strain analysis. In AI patients with poor function, statistical analysis showed significant differences in injury between standard LV regions (F(3.69,44.33) = 3.47, p = 0.017) and levels (F(1.49,17.88) = 4.41, p = 0.037) of the LV, whereas no significant differences were seen in the group with normal cardiac function.
conclusionsPatients with poor function, as defined by multiparametric systolic strain z scores, exhibit a consistent, heterogeneous pattern of contractile injury in which the septum and posterior regions at the base are most injured.
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